{"id":"W2510642606","doi":"10.1093/infdis/jiw357","title":"Alterations in Systemic Extracellular Heme and Hemopexin Are Associated With Adverse Clinical Outcomes in Ugandan Children With Severe Malaria","year":2016,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Alberta; Toronto General Hospital; University Health Network","funders":"Canadian Institutes of Health Research; Massachusetts General Hospital","keywords":"Interquartile range; Medicine; Hemopexin; Gastroenterology; Internal medicine; Heme; Malaria; Immunology; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005243011,0.0004294315,0.0004524417,0.0006655079,0.0006514342,0.0006716269,0.0002918507,0.0003029722,0.0009762755],"category_scores_gemma":[0.002722299,0.0003797442,0.0002057189,0.001078565,0.0007900519,0.0004873772,0.001027124,0.00086284,0.0001118909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005861846,"about_ca_system_score_gemma":0.0005537613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005354032,"about_ca_topic_score_gemma":0.006852732,"domain_scores_codex":[0.999413,0.0001952608,0.00006732996,0.00009273767,0.00007323208,0.0001584174],"domain_scores_gemma":[0.9985241,0.0001482561,0.0009726562,0.00003885763,0.0001195387,0.0001966164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007507279,0.00001784957,0.9975349,0.00003607298,0.00002233087,0.0002013923,0.0004964671,0.00003017942,0.0001534391,0.00002010044,0.0001094084,0.001302911],"study_design_scores_gemma":[0.000004640126,0.00009935152,0.9976552,0.00003918657,0.00001602766,0.0007246558,0.001121616,0.00006723583,0.00004793575,0.00003065092,0.0001886744,0.000004830612],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993043,0.0003671772,0.00003837307,0.00004180656,0.000003323705,0.00000738361,0.00009136321,0.000001874514,0.0001444119],"genre_scores_gemma":[0.9996107,0.00018207,0.00008038242,0.00001717582,0.000003158636,0.00001119514,0.00006477284,9.297644e-7,0.00002954403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005354032,"threshold_uncertainty_score":0.01064575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006710807950102116,"score_gpt":0.2377132186361978,"score_spread":0.2310024106860957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}