{"id":"W2510646213","doi":"10.1111/hae.12994","title":"TRUST trial: BAY 86‐6150 use in haemophilia with inhibitors and assessment for immunogenicity","year":2016,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"Novo Nordisk; Biogen; CSL Behring; Roche; Bayer","keywords":"Immunogenicity; Medicine; Bay; Haemophilia; Immunology; Pediatrics; Antigen; Geography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001358376,0.0006076275,0.0009303458,0.0002133956,0.0002538072,0.0009139986,0.0004317778,0.001245517,0.006281045],"category_scores_gemma":[0.0008585487,0.0002218676,0.0008473965,0.000393859,0.0006800584,0.0005698878,0.0002928827,0.001232576,0.0009170924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007324769,"about_ca_system_score_gemma":0.001072077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001037673,"about_ca_topic_score_gemma":0.002743324,"domain_scores_codex":[0.9994268,0.0002944052,0.00004507003,0.00006202576,0.00008047408,0.00009128227],"domain_scores_gemma":[0.9991173,0.0001534441,0.0003038779,0.00008084964,0.0000850147,0.0002595168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8053934,0.006601082,0.0137732,0.002488775,0.001340919,0.000850976,0.0002443166,0.001564524,0.03881857,0.001178628,0.01700855,0.1107371],"study_design_scores_gemma":[0.5867379,0.3463512,0.03019533,0.0003541368,0.001176898,0.002197002,0.00008737091,0.001454677,0.011509,0.0005304843,0.01934187,0.00006424087],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779555,0.00678589,0.0006170043,0.0009424464,0.0002099728,0.002957963,0.002245791,0.0001267627,0.008158665],"genre_scores_gemma":[0.9846604,0.002862414,0.00114074,0.0009019453,0.0002376044,0.002135908,0.002268852,0.00003692444,0.005755152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006281045,"threshold_uncertainty_score":0.02101219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0452430128399501,"score_gpt":0.3215325868200062,"score_spread":0.2762895739800562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}