{"id":"W2511116188","doi":"10.1371/journal.pone.0161573","title":"The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Institut National de la Recherche Agronomique; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Centre National de la Recherche Scientifique; European Commission; Forest Research","keywords":"Proteases; Cathepsin; Proteolysis; Microbiology; Biology; Biochemistry; Beta defensin; Cathepsin L; Defensin; Protease; Antimicrobial peptides; Chemistry; Antimicrobial; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006179063,0.0002280766,0.0001522654,0.0001203243,0.0000945193,0.000235537,0.0001425763,0.0002870267,0.0005875909],"category_scores_gemma":[0.0001386203,0.00009255271,0.000225082,0.00008223655,0.000175898,0.0001217745,0.000121274,0.000300378,0.0002448708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001255963,"about_ca_system_score_gemma":0.00006083689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003364657,"about_ca_topic_score_gemma":0.0003083307,"domain_scores_codex":[0.9999183,0.000009783031,0.000005957528,0.00002548261,0.0000193533,0.00002110209],"domain_scores_gemma":[0.9998947,0.00001698413,0.00002908397,0.00001293722,0.00002081612,0.00002539956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005947632,0.0000033897,0.0004953952,0.00001695241,0.000003626401,0.00007780661,0.000008336217,0.0000259426,0.9988729,0.00001718819,0.00001239827,0.0004067064],"study_design_scores_gemma":[0.000009933585,0.0003896549,0.03250051,0.000009573173,0.00001831302,0.002012799,0.00008721915,0.0008906192,0.9611748,0.00006508888,0.002833103,0.000008307511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982185,0.0005322907,0.0006512134,0.00002913243,0.000006864989,0.000004105375,0.0001744513,0.00001251974,0.0003707464],"genre_scores_gemma":[0.9975814,0.0001439616,0.0007615676,0.00003938996,0.000003857153,0.000004592222,0.0006338046,0.00001041743,0.0008210881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005875909,"threshold_uncertainty_score":0.001965642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02947201559224262,"score_gpt":0.2202360624825591,"score_spread":0.1907640468903165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}