{"id":"W2511294319","doi":"10.1159/000447832","title":"RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production","year":2016,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"Fonds National de la Recherche Luxembourg; Alexander von Humboldt-Stiftung","keywords":"IRF7; Interferon regulatory factors; Interferon; IRF3; Cell biology; Innate immune system; IκB kinase; Biology; Signal transduction; Gene knockdown; IRF1; FADD; Interferon type I; NF-κB; Transcription factor; Immune system; Virology; Immunology; Programmed cell death; Apoptosis; Caspase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002118278,0.0004687664,0.0002240732,0.0002071953,0.0002329763,0.0003961044,0.0002810173,0.0003428604,0.002892596],"category_scores_gemma":[0.0001212412,0.0001659327,0.0005200893,0.00009975675,0.0002628551,0.0001939735,0.0003634307,0.0007273389,0.001690718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005199648,"about_ca_system_score_gemma":0.0002905811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002382683,"about_ca_topic_score_gemma":0.0002982546,"domain_scores_codex":[0.9997521,0.00003164352,0.00002457626,0.00005570266,0.00006632972,0.00006963549],"domain_scores_gemma":[0.9998838,0.00001735027,0.00003387099,0.00002153612,0.00001935767,0.00002411287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008770173,0.00001730796,0.0001839265,0.00005051892,0.000003340375,0.00004001184,0.000006586129,0.00002698405,0.9989316,0.00007753554,0.00004514197,0.0005293736],"study_design_scores_gemma":[0.000020241,0.00008194525,0.003009454,0.000008561495,0.000008972283,0.0003173553,0.000023304,0.0007474326,0.9937483,0.00005819906,0.001972648,0.000003526057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787393,0.003823459,0.01068152,0.0003031196,0.0001032853,0.00006985341,0.001656617,0.0002052634,0.004417644],"genre_scores_gemma":[0.9883472,0.0009186412,0.00460254,0.00008381803,0.00002110627,0.00007454311,0.002222375,0.00002909473,0.003700644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002892596,"threshold_uncertainty_score":0.009676635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006739443979933146,"score_gpt":0.2026910762264502,"score_spread":0.195951632246517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}