{"id":"W2511294319","doi":"10.1159/000447832","title":"RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production","year":2016,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"Fonds National de la Recherche Luxembourg; Alexander von Humboldt-Stiftung","keywords":"IRF7; Interferon regulatory factors; Interferon; IRF3; Cell biology; Innate immune system; IκB kinase; Biology; Signal transduction; Gene knockdown; IRF1; FADD; Interferon type I; NF-κB; Transcription factor; Immune system; Virology; Immunology; Programmed cell death; Apoptosis; Caspase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000874,0.0001685389,0.0002059407,0.00003447583,0.000112724,0.000005634784,0.0001020697,0.0003001318,0.0003327432],"category_scores_gemma":[0.000120426,0.0001094355,0.00003510391,0.00003990095,0.0006449691,0.00004739901,0.0001255069,0.0001487515,0.0001428489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001395522,"about_ca_system_score_gemma":0.00002473542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003271567,"about_ca_topic_score_gemma":4.702451e-7,"domain_scores_codex":[0.9991256,0.00009398437,0.0001562461,0.0003738181,0.00001409653,0.0002362614],"domain_scores_gemma":[0.9995731,0.00007767473,0.0000642968,0.0002109246,0.00004996155,0.00002409447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005847824,0.00003887405,0.0003654736,0.00003983672,0.0000769078,0.000001631907,0.00007960867,2.221993e-8,0.9947137,0.00005667573,0.001276951,0.002765588],"study_design_scores_gemma":[0.0005033842,0.0002435343,0.001459831,0.0000572293,0.00002290676,0.00006131067,0.0000887533,5.241914e-7,0.9922857,0.0001331223,0.004983686,0.000159965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930676,0.005556031,0.00001090615,0.0004710687,0.0005911149,0.00007290358,0.000007416902,0.0000454278,0.0001775186],"genre_scores_gemma":[0.9907365,0.0007897317,0.00001136132,0.00006366435,0.00009246591,0.000007011547,0.00005551118,0.00001078209,0.008233014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008055495,"threshold_uncertainty_score":0.4462648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006739443979933146,"score_gpt":0.2026910762264502,"score_spread":0.195951632246517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}