{"id":"W2511464803","doi":"10.7164/antibiotics.57.173","title":"Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 I. Taxonomy, Fermentation, Isolation and Screening","year":2004,"lang":"en","type":"article","venue":"The Journal of Antibiotics","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nutrasource","funders":"","keywords":"Streptomyces; Fermentation; Biology; In vitro; Streptomycetaceae; Microbiology; Cell culture; Bacteria; IC50; Cell growth; Biochemistry; Actinomycetales; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001529987,0.00009884768,0.0001723757,0.00003309681,0.00007038379,0.00001894171,0.0001210099,0.00007593888,0.000005475192],"category_scores_gemma":[0.000027096,0.00006853051,0.00005914449,0.00006611703,0.00008851269,0.00001562878,0.00002650879,0.00009027736,3.134298e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007350899,"about_ca_system_score_gemma":0.00008946007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001584169,"about_ca_topic_score_gemma":0.0001295624,"domain_scores_codex":[0.9993646,0.00002966387,0.0002887559,0.00008556972,0.0001277661,0.0001036302],"domain_scores_gemma":[0.9992714,0.00001167932,0.0003991001,0.0001129954,0.0001435828,0.00006121986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003719022,0.00003799313,0.0059924,0.00001368209,0.0002652756,0.000001193463,0.00164706,0.002245504,0.9811649,0.00006618425,0.001844903,0.00634905],"study_design_scores_gemma":[0.002021724,0.0003562881,0.02218034,0.0001178185,0.0002805877,0.00006779639,0.002863471,0.00002467779,0.9601806,0.0004284527,0.01132802,0.0001502527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787582,0.01110555,0.009531103,0.0001460001,0.0003016322,0.00007349722,0.00002126727,0.000001926728,0.00006082049],"genre_scores_gemma":[0.9802231,0.01088233,0.007935479,0.00007880471,0.0007932446,1.222908e-8,0.00001640195,0.000008330851,0.00006233685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02098428,"threshold_uncertainty_score":0.2794593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01708411017657662,"score_gpt":0.2402723546478263,"score_spread":0.2231882444712497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}