{"id":"W2511464803","doi":"10.7164/antibiotics.57.173","title":"Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 I. Taxonomy, Fermentation, Isolation and Screening","year":2004,"lang":"en","type":"article","venue":"The Journal of Antibiotics","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nutrasource","funders":"","keywords":"Streptomyces; Fermentation; Biology; In vitro; Streptomycetaceae; Microbiology; Cell culture; Bacteria; IC50; Cell growth; Biochemistry; Actinomycetales; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001164506,0.0007383117,0.0003962043,0.0006412462,0.0001660789,0.000332754,0.0001910482,0.0002236288,0.0006903608],"category_scores_gemma":[0.0002359922,0.0001365263,0.0002005195,0.0005368341,0.0001755018,0.0002546027,0.0002648422,0.0004129402,0.0006259102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001315948,"about_ca_system_score_gemma":0.0003541945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003355708,"about_ca_topic_score_gemma":0.0006243254,"domain_scores_codex":[0.999871,0.000016587,0.00002365169,0.00002375918,0.00004743585,0.00001763985],"domain_scores_gemma":[0.9998543,0.00001910017,0.00003693531,0.00001414476,0.00003538132,0.00004007271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002887534,0.00005109912,0.0014623,0.0001721844,0.00001140956,0.0002234024,0.00001998351,0.000221098,0.9736572,0.00006021493,0.0001499233,0.02368241],"study_design_scores_gemma":[0.00007454539,0.001817718,0.01494694,0.00005423318,0.00008639716,0.001567168,0.00008125835,0.0004929332,0.9630915,0.0001188083,0.01765262,0.00001584048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9446108,0.02483117,0.01257615,0.000381538,0.0001411738,0.0006002484,0.006289344,0.0004963794,0.0100731],"genre_scores_gemma":[0.9368522,0.0140099,0.02573434,0.0001916977,0.0001063283,0.0003210296,0.01770958,0.00005092337,0.005024081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007383117,"threshold_uncertainty_score":0.002309501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01708411017657662,"score_gpt":0.2402723546478263,"score_spread":0.2231882444712497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}