{"id":"W2511688517","doi":"10.1016/j.tim.2016.08.005","title":"Color Me Infected: Painting Cellular Chromatin with a Viral Histone Mimic","year":2016,"lang":"en","type":"letter","venue":"Trends in Microbiology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Chromatin; Biology; Histone; Cell biology; Cell; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003665658,0.0004175372,0.0002366977,0.0001133937,0.0005005677,0.0009365613,0.0005112262,0.00373517,0.007658011],"category_scores_gemma":[0.0009922826,0.0002335726,0.000332674,0.0000774823,0.0008329381,0.0005187006,0.0004172392,0.003403727,0.001936419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006293878,"about_ca_system_score_gemma":0.0001984696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004180919,"about_ca_topic_score_gemma":0.0006288101,"domain_scores_codex":[0.9998392,0.00004078495,0.000007887424,0.00002745886,0.00004815716,0.00003652733],"domain_scores_gemma":[0.9997953,0.0001086061,0.00001576748,0.00003424566,0.00001414366,0.0000320369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002798157,0.0003897382,0.002427038,0.0003565125,0.0001398913,0.02215787,0.0004344647,0.001233052,0.5527362,0.04603478,0.2669576,0.1043347],"study_design_scores_gemma":[0.0006188903,0.001091063,0.002637288,0.00006532631,0.0001269963,0.02634534,0.0003220657,0.007546141,0.3453826,0.02184309,0.5939368,0.00008430328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.1982186,0.01775365,0.03956594,0.5553319,0.03888526,0.0003339951,0.0005355602,0.001717824,0.1476573],"genre_scores_gemma":[0.7493202,0.007496339,0.01513987,0.07164885,0.005202637,0.0002035455,0.0003010049,0.0002277409,0.1504598],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.007658011,"threshold_uncertainty_score":0.02561855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01149696385128429,"score_gpt":0.2765864346413261,"score_spread":0.2650894707900418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}