{"id":"W2511688517","doi":"10.1016/j.tim.2016.08.005","title":"Color Me Infected: Painting Cellular Chromatin with a Viral Histone Mimic","year":2016,"lang":"en","type":"letter","venue":"Trends in Microbiology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Chromatin; Biology; Histone; Cell biology; Cell; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004814047,0.0006344925,0.0007086511,0.0005788096,0.00008794584,0.00002315288,0.0007256999,0.001742946,0.0006613241],"category_scores_gemma":[0.00003938295,0.0004921976,0.0002017818,0.0002587732,0.0005883079,0.000003878464,0.0002705292,0.001174106,0.0001277984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001999762,"about_ca_system_score_gemma":0.0002238463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005499617,"about_ca_topic_score_gemma":0.0005738029,"domain_scores_codex":[0.9962739,0.0007516929,0.0005235131,0.00113543,0.0001153202,0.001200133],"domain_scores_gemma":[0.9985403,0.00007067493,0.0002988346,0.0009294748,0.00009715655,0.000063528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00062229,0.00003360325,0.0001135903,0.00003946447,0.0001508886,0.0001812874,0.00002561159,0.000003647872,0.7371561,8.830513e-7,0.2584949,0.00317773],"study_design_scores_gemma":[0.001810001,0.003611733,0.00002703232,0.00008687187,0.0000327894,0.0001421012,0.000005211878,0.000004622475,0.4272269,0.00001077651,0.5663767,0.0006652381],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9365994,0.001791597,0.00009115284,0.05941542,0.0003163216,0.0003978135,0.0003518231,0.00006144043,0.0009750559],"genre_scores_gemma":[0.4721191,0.0005799143,0.002048354,0.4091615,0.0128174,0.0008217565,0.03052029,0.001032792,0.07089893],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4644803,"threshold_uncertainty_score":0.9997529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01149696385128429,"score_gpt":0.2765864346413261,"score_spread":0.2650894707900418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}