{"id":"W2511827811","doi":"10.1158/1557-3265.ovcasymp14-poster-biol-1349","title":"Abstract POSTER-BIOL-1349: The oncogenic role of DICER1 RNase IIIb domain mutations in ovarian sertoli-leydig cell tumors","year":2015,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Biology; microRNA; Cancer research; Germline mutation; Somatic cell; Germline; Genetics; Gene; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001915524,0.0002453096,0.0001709111,0.0003240028,0.0002317969,0.0002085531,0.0001516054,0.0004459702,0.01217107],"category_scores_gemma":[0.0001284018,0.00008079449,0.00018191,0.0001290267,0.0001237028,0.0001067907,0.000244514,0.0003526098,0.002364625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002430309,"about_ca_system_score_gemma":0.0001156473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002569244,"about_ca_topic_score_gemma":0.0002525715,"domain_scores_codex":[0.9999253,0.00001237118,0.000008284418,0.00002236567,0.00001679404,0.00001502849],"domain_scores_gemma":[0.999928,0.00001136971,0.000008511009,0.000005210486,0.00001101254,0.00003598147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002831722,0.000364071,0.043563,0.0006322691,0.0001187356,0.039632,0.0002260376,0.0007161033,0.7767838,0.002204704,0.03391591,0.09901176],"study_design_scores_gemma":[0.0004205495,0.002132155,0.2048712,0.00009510472,0.0001983416,0.1183989,0.0002048186,0.002885459,0.4805043,0.001586155,0.1886437,0.0000594037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9471129,0.003607973,0.003810185,0.002476067,0.0007856375,0.0001756309,0.003940051,0.0004913122,0.03760028],"genre_scores_gemma":[0.9650675,0.001077034,0.002054917,0.0004448302,0.0002680326,0.00004432741,0.002565375,0.0001076212,0.02837028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01217107,"threshold_uncertainty_score":0.04071623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.196557835006397,"score_gpt":0.4937086988202837,"score_spread":0.2971508638138867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}