{"id":"W2511866626","doi":"10.1371/journal.pone.0162132","title":"A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Malaria Research and Control","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Medical Research Council; University of California, San Francisco; National Institutes of Health; International Development Research Centre; Burnet Institute","keywords":"Plasmodium chabaudi; Immunity; Parasitemia; Immune system; Immunology; Biology; Asymptomatic; Malaria; Acquired immune system; Plasmodium (life cycle); Chronic infection; Cellular immunity; Virology; Plasmodium falciparum; Medicine; Parasite hosting; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005615916,0.0001002778,0.0003135432,0.0001258136,0.00004842232,0.000005398937,0.0001446801,0.00006122728,0.0001298475],"category_scores_gemma":[0.0004799402,0.00005736117,0.00008470273,0.0001278249,0.00005776244,0.00005818707,0.00008471266,0.00009666737,0.00001817304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001551019,"about_ca_system_score_gemma":0.0001817822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007532402,"about_ca_topic_score_gemma":0.00003180316,"domain_scores_codex":[0.998624,0.00008677562,0.0003265189,0.0001473313,0.0005836492,0.0002317346],"domain_scores_gemma":[0.9989927,0.000136716,0.0001518981,0.0004837699,0.0001461647,0.00008868599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001374135,0.0008761754,0.01765158,0.0002287026,0.0003133499,4.397882e-7,0.00009078667,0.00002000694,0.9789714,0.0001694486,0.00002187384,0.000282106],"study_design_scores_gemma":[0.003882241,0.0007711892,0.2161253,0.001383955,0.0001518493,0.00000130544,0.000005034633,0.004419764,0.7730378,0.0001511577,0.000004114636,0.00006626629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995333,0.0000479262,0.0007204175,0.002743924,0.00001206617,0.0009061158,0.0000252988,0.00002029831,0.0001909616],"genre_scores_gemma":[0.9974269,0.00002170473,0.000425013,0.00004000804,0.00002614543,0.00009165848,0.000002201841,0.00001549996,0.001950817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2059336,"threshold_uncertainty_score":0.2339121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04934954397545946,"score_gpt":0.2854621100686282,"score_spread":0.2361125660931687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}