{"id":"W2511866626","doi":"10.1371/journal.pone.0162132","title":"A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Malaria Research and Control","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Medical Research Council; University of California, San Francisco; National Institutes of Health; International Development Research Centre; Burnet Institute","keywords":"Plasmodium chabaudi; Immunity; Parasitemia; Immune system; Immunology; Biology; Asymptomatic; Malaria; Acquired immune system; Plasmodium (life cycle); Chronic infection; Cellular immunity; Virology; Plasmodium falciparum; Medicine; Parasite hosting; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002271683,0.0005802167,0.0004291837,0.0004532341,0.0003891048,0.0002931984,0.0004459987,0.0006572151,0.001994186],"category_scores_gemma":[0.0001222495,0.0002235344,0.0002320583,0.0001919811,0.0006651503,0.0003892118,0.0003472888,0.001305337,0.000311918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003698475,"about_ca_system_score_gemma":0.0005896846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007612279,"about_ca_topic_score_gemma":0.001188083,"domain_scores_codex":[0.9998689,0.0000232317,0.00001040561,0.00003818694,0.00002479379,0.00003454222],"domain_scores_gemma":[0.999833,0.00001742354,0.00004256237,0.00002501898,0.00001055983,0.00007141892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001481912,0.001012462,0.0004833115,0.0001417601,0.0000135343,0.0005244581,0.0001050642,0.0004273501,0.9886155,0.002946367,0.0006278423,0.003620469],"study_design_scores_gemma":[0.002372885,0.06966311,0.0249129,0.0002546467,0.0002679618,0.01762162,0.0005437724,0.01300328,0.7941275,0.00681033,0.07025391,0.0001680531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.966066,0.002050234,0.02356246,0.0008239163,0.0002936106,0.0008099723,0.0011857,0.0003414854,0.004866715],"genre_scores_gemma":[0.9690238,0.00190108,0.01917019,0.0004365943,0.00008711416,0.001025733,0.0008946027,0.00004419402,0.0074168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001994186,"threshold_uncertainty_score":0.00667125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04934954397545946,"score_gpt":0.2854621100686282,"score_spread":0.2361125660931687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}