{"id":"W2512024885","doi":"10.1083/jcb.201501003","title":"5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion","year":2016,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Susan G. Komen for the Cure","keywords":"Invadopodia; Biology; Inositol; Cell biology; Cancer cell; Cancer; Cell; Phosphatase; Cancer research; Biochemistry; Phosphorylation; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001283961,0.0003057177,0.0001654673,0.00013263,0.0002286196,0.000349368,0.0001597361,0.0001957639,0.001145324],"category_scores_gemma":[0.0001025875,0.0001724525,0.0002610208,0.00008632603,0.0001594024,0.0002448338,0.0003328644,0.0003626402,0.0004846601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004022106,"about_ca_system_score_gemma":0.0002599804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007942788,"about_ca_topic_score_gemma":0.001560257,"domain_scores_codex":[0.9999355,0.000009776119,0.000003916369,0.00001608754,0.0000193555,0.00001536565],"domain_scores_gemma":[0.9999604,0.000004098398,0.000009786857,0.000005167852,0.000006602035,0.00001398211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003612932,0.000008192044,0.0004098406,0.00001701416,0.000004794893,0.0001078679,0.000008874133,0.0001498886,0.9984087,0.0001883951,0.00005924905,0.0006010463],"study_design_scores_gemma":[0.00001804204,0.00006570944,0.01734465,0.000004847501,0.00001087077,0.0004958431,0.00004362622,0.005844126,0.970358,0.000129128,0.005679131,0.000006076396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992685,0.001143715,0.003751181,0.0001435973,0.0000189054,0.00001494288,0.0001553865,0.00007808983,0.002009194],"genre_scores_gemma":[0.9936713,0.0005343388,0.002080393,0.00004740392,0.00000564053,0.00001665133,0.0002416433,0.00001273616,0.003389824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001145324,"threshold_uncertainty_score":0.003831506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01877095868844833,"score_gpt":0.2719870414677265,"score_spread":0.2532160827792782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}