{"id":"W2512248298","doi":"10.1038/nmicrobiol.2016.142","title":"Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA","year":2016,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"Arbutus Biopharma (Canada)","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Ebolavirus; Virology; Small interfering RNA; Ebola virus; Viral replication; Viral load; Medicine; RNA interference; Biology; Immunology; Virus; RNA; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001347629,0.0001691079,0.0003821523,0.0002044605,0.00008265733,0.000005878819,0.00007647928,0.0005335109,0.0002909723],"category_scores_gemma":[0.00006586198,0.00009318622,0.00008225813,0.0002470946,0.0002217028,0.00007365994,0.00005371754,0.0005289966,0.00004652196],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009403074,"about_ca_system_score_gemma":0.00007554959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006898392,"about_ca_topic_score_gemma":0.0005558454,"domain_scores_codex":[0.9989868,0.00007768389,0.0002464321,0.0003297444,0.00006591088,0.000293444],"domain_scores_gemma":[0.9991882,0.00007372764,0.00009170589,0.0002899746,0.0002815716,0.00007484791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004719866,0.0001150642,0.03091493,0.00002632401,0.0001104945,0.000008884567,0.00002834534,0.000001504222,0.9630151,0.00004784341,0.0004362957,0.004823217],"study_design_scores_gemma":[0.002801385,0.001238327,0.1186104,0.000201973,0.00005216492,0.00009733113,0.000005632744,0.000003211366,0.8677806,0.00004128261,0.009037135,0.0001305772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976285,0.0002727132,0.0001831543,0.0003954935,0.0001931537,0.0003443499,0.00008675456,0.00006380468,0.0008320682],"genre_scores_gemma":[0.9981761,0.0001114807,0.0004519425,0.0001397137,0.0001690136,0.00001330532,0.0001658987,0.00002434438,0.0007481753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09523453,"threshold_uncertainty_score":0.4114925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006544041911471152,"score_gpt":0.3133056437284029,"score_spread":0.3067616018169317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}