{"id":"W2512557155","doi":"10.1016/s1474-4422(16)30192-2","title":"Safety and efficacy of amiselimod in relapsing multiple sclerosis (MOMENTUM): a randomised, double-blind, placebo-controlled phase 2 trial","year":2016,"lang":"en","type":"article","venue":"The Lancet Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"Mitsubishi Tanabe Pharma Corporation","keywords":"Medicine; Multiple sclerosis; Placebo; Clinical endpoint; Internal medicine; Population; Clinical trial; Randomized controlled trial; Interferon beta-1a; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002138194,0.002352408,0.003815674,0.0006528249,0.0007308495,0.001265248,0.0008419721,0.002947342,0.007221316],"category_scores_gemma":[0.002489603,0.0008730619,0.002327128,0.000459808,0.00162189,0.001786371,0.0006313527,0.002627972,0.001301414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006264371,"about_ca_system_score_gemma":0.001005735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008122296,"about_ca_topic_score_gemma":0.001310908,"domain_scores_codex":[0.9992988,0.0003219192,0.00006050114,0.0001469723,0.00006137635,0.0001104307],"domain_scores_gemma":[0.9989933,0.000322359,0.0002419467,0.00008776321,0.00006605806,0.0002884701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9885787,0.002029094,0.000321991,0.0004465329,0.0005943821,0.00002909216,0.00003130885,0.00008341146,0.001519892,0.00006036791,0.0003156059,0.005989642],"study_design_scores_gemma":[0.9757736,0.02260941,0.0008629956,0.00002356688,0.0002900726,0.00001375021,0.00001097445,0.00006582182,0.00009369989,0.00006215514,0.0001856761,0.000008110956],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826461,0.008198062,0.0005742877,0.0009065816,0.0008056282,0.003410478,0.001072671,0.0001544669,0.002231787],"genre_scores_gemma":[0.9818749,0.0047815,0.001437879,0.001511127,0.001016948,0.005398802,0.001166243,0.00003009436,0.002782578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007221316,"threshold_uncertainty_score":0.0241577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1111109555709529,"score_gpt":0.3488235848093346,"score_spread":0.2377126292383817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}