{"id":"W2512772018","doi":"10.1021/acs.analchem.6b03030","title":"Tailored Extraction Procedure Is Required To Ensure Recovery of the Main Lipid Classes in Whole Blood When Profiling the Lipidome of Dried Blood Spots","year":2016,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Canada Research Chairs; Canada Foundation for Innovation","keywords":"Lipidome; Chemistry; Dried blood; Profiling (computer programming); Lipidomics; Chromatography; Whole blood; Computational biology; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016016,0.001162672,0.001094258,0.0008882296,0.0006562273,0.000950951,0.0005351063,0.001185693,0.002276845],"category_scores_gemma":[0.001889602,0.0004807573,0.0005608986,0.0007564591,0.0006966983,0.0007199685,0.0005163436,0.001268549,0.003272087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002111488,"about_ca_system_score_gemma":0.0005288001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005871329,"about_ca_topic_score_gemma":0.001065857,"domain_scores_codex":[0.9987507,0.0002308569,0.0001365094,0.0003742037,0.0003746599,0.0001330006],"domain_scores_gemma":[0.9990185,0.0003382176,0.0001387648,0.0001833945,0.0002771848,0.00004391769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005759168,0.00002638412,0.0002867928,0.0001122378,0.00001597201,0.00009555509,0.00003633301,0.00003434617,0.9948902,0.00006945398,0.0001519928,0.004222975],"study_design_scores_gemma":[0.00001479826,0.0001902634,0.006516484,0.00003736845,0.00005498477,0.0008677474,0.00007565102,0.0008203296,0.982335,0.0002864544,0.00876895,0.00003200905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3308863,0.009115249,0.6451591,0.0009727689,0.0008760976,0.002028028,0.003009564,0.002577376,0.00537541],"genre_scores_gemma":[0.2749905,0.009724928,0.6944747,0.001936839,0.0003367443,0.002832837,0.006328137,0.0008756901,0.008499578],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002276845,"threshold_uncertainty_score":0.008470178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072259569126002,"score_gpt":0.2471523823467316,"score_spread":0.2364297866554715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}