{"id":"W2513049377","doi":"10.1038/ncomms12506","title":"Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":123,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs","keywords":"T-cell receptor; Antigen; clone (Java method); Biology; Streptococcus pyogenes; T cell; Microbiology; Cell biology; Genetics; Gene; Bacteria; Staphylococcus aureus; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001163853,0.0001922533,0.0001998384,0.0002454174,0.0005802232,0.00002749018,0.0005862165,0.0003404498,0.0003877522],"category_scores_gemma":[0.0001983366,0.0001442304,0.00008111336,0.0002307816,0.0002803965,0.0001136436,0.0001741537,0.0005665298,0.0003343538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007030097,"about_ca_system_score_gemma":0.00004102006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001049349,"about_ca_topic_score_gemma":0.0003492705,"domain_scores_codex":[0.9987979,0.0003743696,0.0002700802,0.0002777883,0.0000420581,0.0002377956],"domain_scores_gemma":[0.9980913,0.0005266794,0.0001407594,0.0009862775,0.0002149621,0.00004004492],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000573137,0.00009901288,0.0006464363,0.000002982931,0.00009333251,4.647072e-7,0.0001991559,0.000002396481,0.9838439,0.0008461775,0.01046728,0.003741529],"study_design_scores_gemma":[0.001018288,0.0002028746,0.04007912,0.00006201083,0.00004129718,0.000008297357,0.0001260638,0.000008954942,0.7270918,0.00008807753,0.2310424,0.0002307418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9701282,0.008366417,0.001841876,0.009725454,0.002495409,0.001051862,0.0001693735,0.0003978981,0.005823466],"genre_scores_gemma":[0.9927012,0.0003820487,0.0007790275,0.0007324854,0.00002236188,0.00005606693,0.00007520166,0.00002211841,0.005229542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.256752,"threshold_uncertainty_score":0.5881545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01672623654614151,"score_gpt":0.2889801811121387,"score_spread":0.2722539445659972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}