{"id":"W2513082897","doi":"10.1016/j.molimm.2016.08.012","title":"L-Plastin promotes podosome longevity and supports macrophage motility","year":2016,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Canadian Lung Association; American Heart Association","keywords":"Podosome; Motility; Cell biology; Macrophage; Lamellipodium; Actin; Chemotaxis; Actin cytoskeleton; Biology; Cytoskeleton; Cell migration; Cell; In vitro; Receptor; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000215233,0.0002497267,0.0002090193,0.00005244463,0.0000765664,0.00001942788,0.0002665407,0.0002720378,0.0001272625],"category_scores_gemma":[0.0003638305,0.0002019123,0.0001019817,0.00006602805,0.0004907463,0.000007473065,0.0004065946,0.0001072577,0.0000562012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002035237,"about_ca_system_score_gemma":0.00006273251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006846982,"about_ca_topic_score_gemma":0.000006977122,"domain_scores_codex":[0.9983069,0.0002221116,0.0002596623,0.0006491448,0.0001148181,0.0004473104],"domain_scores_gemma":[0.9989111,0.00002370969,0.00009607201,0.0007642545,0.00007017356,0.0001346504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009786725,0.000105952,0.007636842,0.0000178612,0.00008985238,0.0001851231,0.00001331728,4.381992e-7,0.9787152,0.0001973767,0.0001109065,0.01282926],"study_design_scores_gemma":[0.0008993635,0.0003069837,0.04233347,0.00001666932,0.00003019294,0.0001839979,0.000009595634,0.000004986091,0.9494358,0.0007833368,0.005738778,0.0002568279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875815,0.005095673,0.006062977,0.0004521841,0.0001419492,0.0002497946,0.00004566211,0.00003997561,0.0003303132],"genre_scores_gemma":[0.9980423,0.0001654196,0.0007859535,0.0001764105,0.00005063289,0.00002898454,0.00005031664,0.00004233085,0.0006576408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03469662,"threshold_uncertainty_score":0.8233745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003665512563030017,"score_gpt":0.2131861133650179,"score_spread":0.2095206008019879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}