{"id":"W2513212194","doi":"10.1111/apt.13768","title":"Letter: comparative safety and efficacy of infliximab vs. adalimumab in Crohn's disease – should one consider disease location? Authors’ reply","year":2016,"lang":"en","type":"letter","venue":"Alimentary Pharmacology & Therapeutics","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"Medicine; Infliximab; Adalimumab; Crohn's disease; Observational study; Post-hoc analysis; Internal medicine; Disease; Subgroup analysis; Post hoc; Cohort; Clinical trial; Significant difference; Cohort study; Prospective cohort study; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008895979,0.0007468338,0.00269493,0.0009604847,0.001674879,0.002476338,0.003605454,0.02804053,0.006430793],"category_scores_gemma":[0.08073578,0.0006562499,0.001587426,0.001078014,0.002671371,0.004698165,0.001189573,0.02771036,0.005309951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002159079,"about_ca_system_score_gemma":0.002544954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001820985,"about_ca_topic_score_gemma":0.001387511,"domain_scores_codex":[0.9945622,0.002304229,0.001165349,0.0006722273,0.001002291,0.0002936497],"domain_scores_gemma":[0.9436728,0.04056742,0.002503834,0.001383635,0.009914123,0.001958115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005497856,0.00006583713,0.000899983,0.0003564995,0.00009045322,0.0007799894,0.0001631195,0.00009226628,0.0001537671,0.0008701361,0.9849696,0.01100863],"study_design_scores_gemma":[0.001188673,0.0008089348,0.004909087,0.001778099,0.0004273892,0.00679358,0.001139876,0.001180206,0.001432203,0.01215347,0.9678264,0.0003621604],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001092777,0.002889433,0.0001931648,0.9320537,0.06283293,0.0000293308,0.0002261446,0.00007778246,0.0006048165],"genre_scores_gemma":[0.006801461,0.001948461,0.0003714205,0.8893006,0.09961652,0.00008992359,0.00007630508,0.0000488196,0.00174638],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02804053,"threshold_uncertainty_score":0.04704702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04118914863577056,"score_gpt":0.3272570579514191,"score_spread":0.2860679093156485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}