{"id":"W2513283602","doi":"10.1002/1873-3468.12380","title":"Inhibition of <i>Helicobacter pylori</i> Glu‐t<scp>RNA<sup>G</sup></scp><sup>ln</sup> amidotransferase by novel analogues of the putative transamidation intermediate","year":2016,"lang":"en","type":"letter","venue":"FEBS Letters","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval; PROTEO","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Glutamine amidotransferase; Heterotrimeric G protein; Chemistry; Biochemistry; Docking (animal); Stereochemistry; Amino acid; Glutamine; Medicine; G protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004034856,0.0007258857,0.000738794,0.0001844342,0.0001128415,0.00004689811,0.0007034222,0.001067823,0.00003306955],"category_scores_gemma":[0.0001340352,0.0005385946,0.00066523,0.0002047251,0.0004985351,0.00003553529,0.00008457341,0.0006465098,0.00001838189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006295271,"about_ca_system_score_gemma":0.000098397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004981813,"about_ca_topic_score_gemma":0.000003973912,"domain_scores_codex":[0.9963713,0.000471934,0.0009453389,0.000906568,0.0006426679,0.0006621352],"domain_scores_gemma":[0.9980243,0.0001909171,0.0006210829,0.0008590846,0.000212161,0.00009240412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005886898,0.0000459024,0.00003540355,0.0002486461,0.0003130749,0.000008872853,0.0006250183,0.00009549221,0.8333309,0.000005450227,0.1639606,0.001271781],"study_design_scores_gemma":[0.001023585,0.0002448636,0.00004262988,0.0003999484,0.0001931137,0.00001065207,0.00009787333,0.00002719707,0.8594389,0.00005621896,0.1381556,0.0003093881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8304742,0.0004329955,0.04342742,0.1172132,0.0004550152,0.001467929,0.006252292,0.00004502029,0.0002319334],"genre_scores_gemma":[0.6861156,0.0005079394,0.0004583967,0.3026104,0.003329193,0.0002943604,0.005610764,0.0002600378,0.0008133045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1853973,"threshold_uncertainty_score":0.9997066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00947722309515373,"score_gpt":0.207468015995571,"score_spread":0.1979907929004172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}