{"id":"W2513283602","doi":"10.1002/1873-3468.12380","title":"Inhibition of <i>Helicobacter pylori</i> Glu‐t<scp>RNA<sup>G</sup></scp><sup>ln</sup> amidotransferase by novel analogues of the putative transamidation intermediate","year":2016,"lang":"en","type":"letter","venue":"FEBS Letters","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval; PROTEO","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Glutamine amidotransferase; Heterotrimeric G protein; Chemistry; Biochemistry; Docking (animal); Stereochemistry; Amino acid; Glutamine; Medicine; G protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001845947,0.0003548597,0.0002431951,0.00005638103,0.0001717526,0.00020648,0.000310556,0.001679351,0.001663917],"category_scores_gemma":[0.0003431796,0.00008252517,0.0001315931,0.00006639164,0.0002876286,0.0001843381,0.0001055443,0.0009040401,0.001131298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004666835,"about_ca_system_score_gemma":0.0001705089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004401764,"about_ca_topic_score_gemma":0.0005757937,"domain_scores_codex":[0.9998969,0.00002326765,0.000008249904,0.00001537327,0.00003210188,0.00002423399],"domain_scores_gemma":[0.9999076,0.00002976463,0.00001558896,0.000009824259,0.00001669571,0.00002046316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00523484,0.0006582697,0.00315819,0.0006922193,0.00005497463,0.01730329,0.0001823232,0.001136715,0.7961215,0.00733192,0.05966359,0.1084623],"study_design_scores_gemma":[0.0004585845,0.003964436,0.005612426,0.00004755622,0.00004298576,0.01167941,0.0001137864,0.007350999,0.7865163,0.002792278,0.1813915,0.00002979431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.86081,0.02680683,0.004934751,0.04972777,0.008383302,0.0001654391,0.0004389115,0.0003231425,0.04840998],"genre_scores_gemma":[0.9540156,0.007203333,0.002019694,0.007227547,0.001905437,0.00009159499,0.0003057383,0.00003238336,0.02719887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001679351,"threshold_uncertainty_score":0.005566359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00947722309515373,"score_gpt":0.207468015995571,"score_spread":0.1979907929004172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}