{"id":"W2513504681","doi":"10.1158/2326-6066.cir-16-0179","title":"Zeroing in on Tumor-Reactive TILs","year":2016,"lang":"en","type":"letter","venue":"Cancer Immunology Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"","keywords":"Adoptive cell transfer; Cancer immunotherapy; Cancer; Immunotherapy; Cancer research; Adoptive immunotherapy; Tumor cells; Medicine; Immunology; T cell; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.002090629,0.0004854496,0.001123122,0.002547959,0.000173957,0.00005277797,0.0009046586,0.001451845,0.01510027],"category_scores_gemma":[0.0006311296,0.0003792665,0.0002386541,0.0009995439,0.001481411,0.00008973372,0.0004374667,0.0146192,0.00214753],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004094669,"about_ca_system_score_gemma":0.002391878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001392184,"about_ca_topic_score_gemma":0.00008459295,"domain_scores_codex":[0.9925965,0.001352109,0.0005261686,0.0012899,0.00168522,0.002550067],"domain_scores_gemma":[0.9951456,0.002187454,0.000118876,0.001657863,0.0007559775,0.0001342684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002828204,0.00008754373,0.001284342,0.0002219782,0.0005286887,0.006152289,0.000254454,2.165002e-7,0.1741786,0.00003477099,0.7622387,0.05219014],"study_design_scores_gemma":[0.003019698,0.001096122,0.002427039,0.001846502,0.00001839335,0.0001799462,0.00008361944,0.00000259405,0.02393514,0.0003546028,0.9666995,0.0003367873],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.06681279,0.00571347,0.000001721932,0.8585442,0.0009120904,0.002390363,0.00009575296,0.00009805314,0.06543161],"genre_scores_gemma":[0.01887047,0.008032167,0.00002882481,0.4017226,0.01754171,0.004207599,0.0002788427,0.0006910044,0.5486268],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.4831952,"threshold_uncertainty_score":0.9998659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1193831384650377,"score_gpt":0.4404190876862732,"score_spread":0.3210359492212355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}