{"id":"W2513504681","doi":"10.1158/2326-6066.cir-16-0179","title":"Zeroing in on Tumor-Reactive TILs","year":2016,"lang":"en","type":"letter","venue":"Cancer Immunology Research","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"","keywords":"Adoptive cell transfer; Cancer immunotherapy; Cancer; Immunotherapy; Cancer research; Adoptive immunotherapy; Tumor cells; Medicine; Immunology; T cell; Immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002859527,0.0004029818,0.0003952318,0.0001932152,0.0004238405,0.0007574143,0.0002552888,0.001713181,0.004024133],"category_scores_gemma":[0.001236733,0.0001098414,0.0003602605,0.00009772966,0.0004426517,0.0005589891,0.0002450457,0.002888889,0.002687611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008219074,"about_ca_system_score_gemma":0.0002011528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002047893,"about_ca_topic_score_gemma":0.0003228924,"domain_scores_codex":[0.9996231,0.00009836391,0.00002171629,0.00005872883,0.0001001155,0.00009798987],"domain_scores_gemma":[0.9995752,0.0001995418,0.00004053743,0.00007506145,0.00006107524,0.00004856931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002871351,0.0007203134,0.008862596,0.0008844819,0.00008764232,0.0568453,0.0007360335,0.001346163,0.1906367,0.03983763,0.1852876,0.511884],"study_design_scores_gemma":[0.0003508176,0.001773595,0.004031708,0.0001761814,0.0001121081,0.0480159,0.000403703,0.004613767,0.2002003,0.02891541,0.7113643,0.00004211579],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"editorial","genre_scores_codex":[0.4969976,0.02433707,0.05001809,0.184729,0.02773427,0.000565526,0.0006263657,0.003008213,0.2119839],"genre_scores_gemma":[0.8798923,0.003983848,0.00505855,0.0358831,0.006620576,0.0001077393,0.000175602,0.0001230663,0.06815526],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.004024133,"threshold_uncertainty_score":0.01346201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1193831384650377,"score_gpt":0.4404190876862732,"score_spread":0.3210359492212355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}