{"id":"W2513638620","doi":"10.1371/journal.ppat.1005842","title":"An Essential Viral Transcription Activator Modulates Chromatin Dynamics","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Institute of Infection and Immunity; Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Histone; Biology; Chromatin; Cell biology; Gene silencing; Nucleosome; Histone H3; Transcription (linguistics); Transcription factor; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004255303,0.0001362789,0.0001785145,0.00007365708,0.00009469534,0.0000145824,0.00003865,0.00009601877,0.0004174546],"category_scores_gemma":[0.00001849813,0.00008887307,0.00009139092,0.00008004653,0.00004155484,0.0001748128,0.000006264206,0.00005791617,0.0001700012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001633697,"about_ca_system_score_gemma":0.00003829511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002459042,"about_ca_topic_score_gemma":0.00002572174,"domain_scores_codex":[0.9992048,0.00003918128,0.0001609042,0.0002315424,0.0001577316,0.0002058637],"domain_scores_gemma":[0.999477,0.00001595328,0.00003981307,0.0002760613,0.00004952032,0.0001416116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006210073,0.0009105944,0.01297418,0.00001942036,0.0001331856,0.00004562409,0.0001153142,0.000001267109,0.944858,0.0002532292,0.00001207564,0.04061504],"study_design_scores_gemma":[0.006706547,0.001687601,0.1165526,0.0003581749,0.0009087939,0.0001446361,0.0001349186,0.0151626,0.8553046,0.0009213449,0.001534961,0.0005832519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955255,0.00001226182,0.002881489,0.0002249465,0.0001275041,0.0002525038,0.0001570701,0.0001636738,0.0006549988],"genre_scores_gemma":[0.9983421,0.00002139317,0.0009497945,0.00004766411,0.0001794153,0.0000237942,0.00006793498,0.00003174548,0.0003361405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1035784,"threshold_uncertainty_score":0.4570835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01298161554190128,"score_gpt":0.2594012910039484,"score_spread":0.2464196754620471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}