{"id":"W2514241645","doi":"10.1038/srep32495","title":"Myostatin inhibition therapy for insulin-deficient type 1 diabetes","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; York University","keywords":"Myostatin; Internal medicine; Endocrinology; GLUT4; Insulin resistance; Insulin; Skeletal muscle; Diabetes mellitus; Medicine; Glucose uptake; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871164,0.0004313321,0.0004308788,0.0002941026,0.0001686606,0.0001691528,0.000292485,0.0003027008,0.00106331],"category_scores_gemma":[0.00005920781,0.00007873976,0.000287608,0.0001611415,0.0001933532,0.0001841064,0.0001740403,0.0008938502,0.0001844388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001659587,"about_ca_system_score_gemma":0.0002649381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002491038,"about_ca_topic_score_gemma":0.0006916677,"domain_scores_codex":[0.999948,0.00001212727,0.000004736453,0.000009424611,0.00001417716,0.00001152639],"domain_scores_gemma":[0.999964,0.000005025552,0.00001117616,0.000002741015,0.000002775326,0.00001426087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00431211,0.00232664,0.0008528038,0.0004402317,0.00007832244,0.0003805813,0.00003801307,0.000457281,0.9244848,0.0007654116,0.000795048,0.06506871],"study_design_scores_gemma":[0.005696546,0.06692249,0.03254315,0.0004339127,0.0005671367,0.002889061,0.0001462993,0.006524915,0.8269635,0.001381043,0.05585382,0.00007816908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.965835,0.01861846,0.009796477,0.0006245483,0.0004271354,0.0002805626,0.000344225,0.0003320322,0.003741584],"genre_scores_gemma":[0.9636232,0.01935047,0.01131436,0.0005168883,0.0001086648,0.0003025376,0.0006840847,0.00003917987,0.004060519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00106331,"threshold_uncertainty_score":0.003557146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01105885389544355,"score_gpt":0.2476800100351479,"score_spread":0.2366211561397044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}