{"id":"W2514360855","doi":"10.5858/arpa.2012-0720-oa","title":"Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology","year":2013,"lang":"en","type":"article","venue":"Archives of Pathology & Laboratory Medicine","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":428,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Cancer Institute","keywords":"Guideline; Medicine; Anaplastic lymphoma kinase; Lung cancer; Family medicine; Oncology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007197483,0.0001871852,0.000634271,0.0001279015,0.0001087022,0.000002898968,0.000110531,0.00008846525,0.000003597686],"category_scores_gemma":[0.003853431,0.0001247443,0.00007469,0.0002139779,0.0002991642,0.00005633414,0.00004412659,0.00008956058,8.728303e-9],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001636178,"about_ca_system_score_gemma":0.0002251016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00105727,"about_ca_topic_score_gemma":0.0002618843,"domain_scores_codex":[0.9980889,0.0001409227,0.0009967413,0.0003281437,0.0002356912,0.0002096068],"domain_scores_gemma":[0.9932964,0.002480478,0.001669437,0.000175346,0.002330913,0.00004737751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006885352,0.0006553223,0.7176976,0.0002726065,0.001304259,0.000002283688,0.00356822,0.0002247261,0.2600905,0.0002279169,0.006589467,0.008678587],"study_design_scores_gemma":[0.05475611,0.01635418,0.7937823,0.00111811,0.01249956,0.000006626931,0.00804056,0.04971661,0.0577994,0.001862633,0.003524263,0.0005396687],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733121,0.003058807,0.008236839,0.005181707,0.000331226,0.004923491,0.004933245,0.00001161633,0.00001099912],"genre_scores_gemma":[0.9855698,0.0002357925,0.01080032,0.0006097005,0.000216923,0.002022235,0.0004880826,0.00003152059,0.00002561068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2022911,"threshold_uncertainty_score":0.5086925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009531255861994709,"score_gpt":0.3332404848885003,"score_spread":0.3237092290265056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}