{"id":"W2514448720","doi":"10.1038/ng.3646","title":"Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution","year":2016,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1292,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"U.S. National Library of Medicine; National Cancer Institute; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Biology; Chromatin; Haematopoiesis; Stem cell; Lineage (genetic); Genetics; Hematopoietic stem cell; Leukemia; Computational biology; Enhancer; Myeloid; Epigenomics; Cancer research; Gene; Transcription factor; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02055692789550373,"score_gpt":0.2904839785553225,"score_spread":0.2699270506598188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}