{"id":"W2514766623","doi":"10.2337/dc16-0917","title":"Benefits of LixiLan, a Titratable Fixed-Ratio Combination of Insulin Glargine Plus Lixisenatide, Versus Insulin Glargine and Lixisenatide Monocomponents in Type 2 Diabetes Inadequately Controlled on Oral Agents: The LixiLan-O Randomized Trial","year":2016,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":268,"is_retracted":false,"has_abstract":true,"ca_institutions":"LMC Diabetes & Endocrinology (Canada)","funders":"Sanofi","keywords":"Lixisenatide; Medicine; Insulin glargine; Type 2 diabetes; Randomized controlled trial; Diabetes mellitus; Internal medicine; Endocrinology; Basal insulin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000825312,0.000456265,0.001925855,0.0004909741,0.00007412975,0.00003992872,0.0002405094,0.0001794749,0.00005899541],"category_scores_gemma":[0.001407516,0.0002718646,0.0002743537,0.0005169563,0.0002271992,0.0002244732,0.0001389361,0.0001837491,0.00002329177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002210154,"about_ca_system_score_gemma":0.0001066984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006974161,"about_ca_topic_score_gemma":0.00007434619,"domain_scores_codex":[0.9969218,0.000377752,0.001080837,0.0004783937,0.0006209621,0.0005202589],"domain_scores_gemma":[0.9967534,0.00159658,0.0005678426,0.0005214745,0.0004211772,0.0001395381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8954523,0.00259982,0.04259406,0.0008941166,0.003187991,0.00001444937,0.002336915,0.0003329984,0.00357702,0.003857861,0.0012047,0.04394781],"study_design_scores_gemma":[0.9589036,0.003519852,0.01742749,0.0009388697,0.0007934782,1.120753e-7,0.0003103389,0.002174659,0.01501891,0.0001709865,0.0004239347,0.0003177359],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987633,0.004730463,0.000004255959,0.001025168,0.0005538625,0.00501073,0.0001307386,0.00005379197,0.0008580152],"genre_scores_gemma":[0.997107,0.001156775,0.000139225,0.0002016037,0.00009515428,0.0005683628,0.0004354738,0.00005114982,0.0002452547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06345138,"threshold_uncertainty_score":0.9999734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02269637888175718,"score_gpt":0.2615490002325614,"score_spread":0.2388526213508043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}