{"id":"W2514978986","doi":"10.1182/blood.v126.23.571.571","title":"Disruptive ARID1A Mutations in Follicular Lymphoma Impair DNA Repair Efficiency and Are Associated with Favorable Outcome in Patients Receiving First-Line Immunochemotherapy","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"ARID1A; Follicular lymphoma; Lymphoma; Cancer research; Internal medicine; Oncology; Medicine; Aggressive lymphoma; Mutation; Biology; Immunology; Rituximab; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002360416,0.0001479186,0.0001926377,0.00005396614,0.00005046975,0.00001792053,0.00007923554,0.0001135979,0.000001288193],"category_scores_gemma":[0.0002201919,0.000130161,0.00004518394,0.000198976,0.00004100957,0.000007131225,0.00003808987,0.00005879004,8.007356e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006709269,"about_ca_system_score_gemma":0.00008177035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001537874,"about_ca_topic_score_gemma":0.0007104946,"domain_scores_codex":[0.9990359,0.00005330719,0.0002505392,0.0003036468,0.000137085,0.0002195199],"domain_scores_gemma":[0.9994976,0.00001684648,0.0001193457,0.0002048674,0.0001018872,0.00005948346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009225667,0.001064844,0.9943337,0.00001717097,0.00007143118,0.000008721615,0.000645099,0.001883914,0.001453423,0.000001208564,0.00002161029,0.0004066322],"study_design_scores_gemma":[0.01981686,0.001102874,0.9636435,0.000283607,0.00005832759,0.000008297593,0.0006450792,0.003819504,0.009967164,0.0000740648,0.00009867944,0.0004820383],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987857,0.0006552157,0.0001151637,0.00004018465,0.00003072535,0.0002199462,0.00001714928,0.00002510273,0.0001108605],"genre_scores_gemma":[0.999401,0.00004606693,0.0002451522,0.00006486264,0.00001894613,0.00002862677,0.0001021585,0.00002198984,0.0000712321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03069019,"threshold_uncertainty_score":0.5307813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128356392371144,"score_gpt":0.2418024145507276,"score_spread":0.2305188506270162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}