{"id":"W2515222649","doi":"10.1016/j.vaccine.2016.08.009","title":"Delivery of an inactivated avian influenza virus vaccine adjuvanted with poly(D,L-lactic-co-glycolic acid) encapsulated CpG ODN induces protective immune responses in chickens","year":2016,"lang":"en","type":"article","venue":"Vaccine","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Ontario Ministry of Agriculture, Food and Rural Affairs; Canadian Poultry Research Council","keywords":"Adjuvant; Immunogenicity; CpG Oligodeoxynucleotide; Nasal administration; Antibody; PLGA; Immune system; Vaccination; Virology; Avidity; Biology; Microbiology; Virus; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009003705,0.0006630897,0.001430214,0.001667958,0.0002046973,0.00002758017,0.0003970582,0.0003451557,0.0003948096],"category_scores_gemma":[0.002168773,0.0004137734,0.0001292905,0.002081545,0.0001128425,0.000853055,0.0002204108,0.0008589501,0.00007330187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005473776,"about_ca_system_score_gemma":0.0006383108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003753954,"about_ca_topic_score_gemma":0.001090759,"domain_scores_codex":[0.9954856,0.0006065637,0.001158765,0.0008469197,0.0008436634,0.001058455],"domain_scores_gemma":[0.9965014,0.0004542939,0.0005459959,0.001110297,0.001037992,0.0003499855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.06250139,0.0009254033,0.04921632,0.0001441132,0.0006427431,0.0003374734,0.001327154,0.000001645086,0.8724365,0.00002093583,0.00004174483,0.01240456],"study_design_scores_gemma":[0.01328216,0.003099042,0.4689924,0.0007823317,0.00008396379,0.00007625165,0.0004103795,0.0000237321,0.5126647,0.00003757946,0.0002353782,0.0003121481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935582,0.00279414,0.00002818953,0.0007370784,0.00004915025,0.002232062,0.0001393544,0.0002307713,0.0002310306],"genre_scores_gemma":[0.9982951,0.0002702278,0.000306016,0.0003263249,0.0001093788,0.0003546938,0.00002382312,0.0001207519,0.0001936791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.419776,"threshold_uncertainty_score":0.9998314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04130618756529962,"score_gpt":0.342472620451503,"score_spread":0.3011664328862034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}