{"id":"W2515222649","doi":"10.1016/j.vaccine.2016.08.009","title":"Delivery of an inactivated avian influenza virus vaccine adjuvanted with poly(D,L-lactic-co-glycolic acid) encapsulated CpG ODN induces protective immune responses in chickens","year":2016,"lang":"en","type":"article","venue":"Vaccine","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Ontario Ministry of Agriculture, Food and Rural Affairs; Canadian Poultry Research Council","keywords":"Adjuvant; Immunogenicity; CpG Oligodeoxynucleotide; Nasal administration; Antibody; PLGA; Immune system; Vaccination; Virology; Avidity; Biology; Microbiology; Virus; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001858168,0.0003409672,0.0001785634,0.0002147298,0.0001276199,0.0001568538,0.0001623233,0.0003247017,0.0005675713],"category_scores_gemma":[0.0001523402,0.0001514427,0.0002292425,0.00005573925,0.0002493706,0.0002078764,0.00009359361,0.0004950778,0.0001967634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002905537,"about_ca_system_score_gemma":0.0002506686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001684077,"about_ca_topic_score_gemma":0.001672229,"domain_scores_codex":[0.9998974,0.00001401313,0.00000976654,0.00003225472,0.00001647675,0.00003011785],"domain_scores_gemma":[0.9999024,0.00002055359,0.00001946319,0.00001084599,0.00001866545,0.00002806814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003364059,0.00006217699,0.0001526263,0.00002198633,0.000002740833,0.00001922234,0.00002038788,0.00005043238,0.9986681,0.00002428717,0.00001230136,0.0006293506],"study_design_scores_gemma":[0.00006515592,0.003541775,0.003028397,0.000009639706,0.0000321938,0.0001062321,0.0000482379,0.000560599,0.9918394,0.00003066132,0.0007334034,0.000004309253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986613,0.0002369086,0.0005876402,0.00004024748,0.00002557827,0.00001647477,0.0000535996,0.00001381875,0.0003643789],"genre_scores_gemma":[0.996949,0.0002313212,0.0007956708,0.00003305984,0.000009983954,0.00001605501,0.0001260515,0.000006799453,0.00183198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001684077,"threshold_uncertainty_score":0.003348529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04130618756529962,"score_gpt":0.342472620451503,"score_spread":0.3011664328862034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}