{"id":"W2515403730","doi":"10.18632/oncotarget.11939","title":"DOT1L promotes angiogenesis through cooperative regulation of VEGFR2 with ETS-1","year":2016,"lang":"en","type":"article","venue":"Oncotarget","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Tianjin Science and Technology Committee; National Natural Science Foundation of China","keywords":"Angiogenesis; Cell biology; Matrigel; Biology; Gene silencing; Cancer research; Neovascularization; Transcription factor; Histone; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007965714,0.0001285148,0.0001372879,0.00002598024,0.00004322298,0.000005980349,0.00007992655,0.0001286097,0.00009923304],"category_scores_gemma":[0.00003146573,0.00008480284,0.0000567734,0.0001274686,0.0001031428,0.00001096251,0.00003114701,0.00002153596,0.00001059566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000332545,"about_ca_system_score_gemma":0.0001090689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002334344,"about_ca_topic_score_gemma":0.00006235714,"domain_scores_codex":[0.9992146,0.00004702428,0.0001726303,0.0002746852,0.0001424253,0.0001485848],"domain_scores_gemma":[0.9993497,0.00001156867,0.0001253948,0.0002853964,0.000194558,0.0000334521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001966524,0.0000390666,0.006512804,0.00001013535,0.00008172784,3.839743e-7,0.00007794642,0.0002792187,0.9890376,0.0001681908,0.001716686,0.001879529],"study_design_scores_gemma":[0.0007980646,0.0005291908,0.0220161,0.00005590382,0.00002892651,0.000007875238,0.00001481871,0.00003211801,0.9544373,0.0001457295,0.02177121,0.0001627694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877518,0.0006542259,0.00951731,0.0005566655,0.00008142794,0.0002428219,0.00003608343,0.00001536975,0.001144262],"genre_scores_gemma":[0.9951537,0.0001022216,0.002786312,0.00003511743,0.0001796725,0.00002120569,0.00009782303,0.0000247257,0.00159925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03460037,"threshold_uncertainty_score":0.345816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007424850997499691,"score_gpt":0.2344642605646164,"score_spread":0.2270394095671167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}