{"id":"W2515692516","doi":"10.1016/j.bpj.2015.11.1483","title":"Modulation of hERG 1a Trafficking by hERG 1b Subunits in Heart","year":2016,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"hERG; Chemistry; Repolarization; Potassium channel; Long QT syndrome; Protein subunit; Pharmacology; Biophysics; Cell biology; Electrophysiology; Biology; Biochemistry; QT interval; Medicine; Neuroscience; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000264821,0.0001594935,0.0002827152,0.0001294181,0.000260691,0.0007161867,0.0002203898,0.0005392432,0.001660589],"category_scores_gemma":[0.0005633832,0.0001481895,0.0001896228,0.0001074567,0.0002810179,0.0006640959,0.0003087826,0.0006712046,0.0005064216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004599072,"about_ca_system_score_gemma":0.0001463612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004122505,"about_ca_topic_score_gemma":0.0003979595,"domain_scores_codex":[0.9998252,0.000053639,0.00001285852,0.00003122335,0.00002111173,0.00005604243],"domain_scores_gemma":[0.9998883,0.00003777324,0.00001869191,0.00001357082,0.00001339491,0.00002832335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001072434,0.00007138694,0.001323355,0.00007224689,0.00001764041,0.0003232685,0.0001512157,0.0003419773,0.988808,0.001566025,0.000582544,0.005669826],"study_design_scores_gemma":[0.0006436569,0.000972082,0.1058586,0.0001998226,0.0001156824,0.003034784,0.001500139,0.02692331,0.83486,0.005489957,0.02034043,0.00006167958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920928,0.003466581,0.001297628,0.0007989791,0.00009050662,0.000008969106,0.000114853,0.00002717224,0.002102584],"genre_scores_gemma":[0.9971629,0.001103435,0.0004656934,0.0002132006,0.0000256988,0.000009926421,0.0001029846,0.00001844798,0.0008976562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001660589,"threshold_uncertainty_score":0.005555212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01102691857519996,"score_gpt":0.258185873703254,"score_spread":0.247158955128054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}