{"id":"W2515719438","doi":"10.1016/j.virol.2016.08.012","title":"D186/D190 is an allele-dependent determinant of HIV-1 Nef function","year":2016,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Ontario Trillium Foundation","keywords":"Biology; Jurkat cells; Signal transduction; Allele; Cell biology; Genetics; Gene; T cell; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002275559,0.0003925524,0.0003536314,0.0003501316,0.000348213,0.000434299,0.0004205437,0.0004969552,0.00693462],"category_scores_gemma":[0.0003623038,0.0002078986,0.0004359648,0.0001922926,0.0005181283,0.0001999473,0.0004171873,0.0007745979,0.00195115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003111472,"about_ca_system_score_gemma":0.0002139997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007695441,"about_ca_topic_score_gemma":0.0008038495,"domain_scores_codex":[0.9996949,0.00007708336,0.00004137142,0.00004526418,0.00006575607,0.0000755665],"domain_scores_gemma":[0.9995814,0.0001108584,0.0001275191,0.0000391863,0.0000259338,0.0001151007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004535035,0.00006940079,0.000754862,0.00001684401,0.00001747219,0.0004043459,0.0000122741,0.00007336261,0.9966704,0.0002612481,0.0001193944,0.001146833],"study_design_scores_gemma":[0.0002148446,0.0006565385,0.03342446,0.000022218,0.00008076205,0.00517677,0.00011763,0.002640521,0.9499295,0.0003767103,0.007304911,0.00005520434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939418,0.0002922427,0.002105517,0.0001521433,0.00007723584,0.00003260581,0.0007815001,0.00009097761,0.002525825],"genre_scores_gemma":[0.9974911,0.00006834172,0.0007787512,0.00008461971,0.00001706258,0.00001158249,0.0004215789,0.0000940946,0.001033012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00693462,"threshold_uncertainty_score":0.0231986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01691178039858708,"score_gpt":0.253477750860223,"score_spread":0.2365659704616359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}