{"id":"W2515868220","doi":"10.1016/j.nmd.2016.06.303","title":"Upper and lower extremity muscle strength decline over 1 year in a prospective, observational GNE-myopathy natural history study","year":2016,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Natural history study; Observational study; Grip strength; Natural history; Physical therapy; Weakness; Physical medicine and rehabilitation; Muscle strength; Prospective cohort study; Myopathy; Muscle weakness; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001567282,0.0006113088,0.0007170007,0.0007956295,0.001178987,0.0009318832,0.0007254871,0.00128299,0.001212906],"category_scores_gemma":[0.002163256,0.0009584854,0.00108893,0.0009247304,0.0006261748,0.001199431,0.001106916,0.001476695,0.0003713136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004302719,"about_ca_system_score_gemma":0.0004453182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00950375,"about_ca_topic_score_gemma":0.01355855,"domain_scores_codex":[0.9992021,0.0002915103,0.00007436677,0.0002223025,0.00008397513,0.0001258453],"domain_scores_gemma":[0.9982923,0.0002621715,0.0005356388,0.0002443348,0.0001660955,0.000499467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006012454,0.0002404062,0.9978916,0.000009854565,0.0002344966,0.0001262969,0.0001170824,0.0000242955,0.0003359203,0.00001671956,0.00006036665,0.0003418441],"study_design_scores_gemma":[0.00003343732,0.0002927321,0.9990143,0.000004704375,0.00009389524,0.0001600548,0.0002007483,0.00008129777,0.00002239139,0.00001497847,0.00007702412,0.000004474517],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994562,0.000136822,0.00005379734,0.00002396335,0.000006409008,0.00000827282,0.0001768821,0.000001772397,0.0001358582],"genre_scores_gemma":[0.9991055,0.00008254698,0.00006944122,0.00004446214,0.00001169771,0.0000135059,0.0004089481,0.000002095608,0.0002617603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00950375,"threshold_uncertainty_score":0.01889688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01543625226194261,"score_gpt":0.2487007421672731,"score_spread":0.2332644899053305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}