{"id":"W2515934337","doi":"10.1186/s12881-016-0320-4","title":"Acyl-CoA synthetase long-chain 5 genotype is associated with body composition changes in response to lifestyle interventions in postmenopausal women with overweight and obesity: a genetic association study on cohorts Montréal-Ottawa New Emerging Team, and Complications Associated with Obesity","year":2016,"lang":"en","type":"article","venue":"BMC Medical Genetics","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; Montfort Hospital; Agricultural Research Institute of Ontario; University of Ottawa","funders":"Canadian Institutes of Health Research; Genome Canada","keywords":"Overweight; Obesity; Body mass index; Medicine; Genotype; Psychological intervention; Genotyping; Internal medicine; Weight loss; Endocrinology; Biology; Genetics; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005150484,0.0004305269,0.0003791573,0.0005061926,0.00082996,0.0006002528,0.0007353496,0.0004866579,0.00205323],"category_scores_gemma":[0.001293899,0.0003617595,0.0006299618,0.0008560299,0.0003399142,0.000149533,0.0003837594,0.0005138837,0.0001512615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00154209,"about_ca_system_score_gemma":0.001135633,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.4582274,"about_ca_topic_score_gemma":0.5422436,"domain_scores_codex":[0.9996792,0.00004729225,0.0000212,0.0001176749,0.00007286544,0.00006178728],"domain_scores_gemma":[0.9992551,0.00006683182,0.0002844379,0.00006882459,0.0001337983,0.000191009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005146178,0.00003877863,0.9968666,0.00001305307,0.0002197998,0.00007349114,0.0001297425,0.00002293412,0.0008627362,0.00001394901,0.0001688707,0.00107531],"study_design_scores_gemma":[0.00001131106,0.00003370193,0.9997104,0.000002823352,0.00004586541,0.00002246367,0.00004641239,0.00003201622,0.00002585454,0.000003140451,0.00006411313,0.000001955645],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987501,0.0002813711,0.00005271391,0.0000582814,0.000006378441,0.00001954358,0.000510809,0.00000345311,0.0003173303],"genre_scores_gemma":[0.9987895,0.00009835306,0.0001188328,0.00003283346,0.000006695926,0.00002050375,0.0003570874,0.00000285325,0.000573449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5417726,"threshold_uncertainty_score":0.9111204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008965301045909282,"score_gpt":0.250702199538867,"score_spread":0.2417368984929577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}