{"id":"W2516309500","doi":"10.1097/tp.0000000000001394","title":"Influence of Donor and Recipient CYP3A4, CYP3A5, and ABCB1 Genotypes on Clinical Outcomes and Nephrotoxicity in Liver Transplant Recipients","year":2016,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Particle Physics","funders":"","keywords":"Hazard ratio; Medicine; Calcineurin; Internal medicine; Tacrolimus; Confidence interval; Renal function; Gastroenterology; Proportional hazards model; Population; Nephrotoxicity; Kidney transplantation; Transplantation; Liver transplantation; Urology; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002346079,0.0001881526,0.0004018132,0.0001575284,0.00004025322,0.000008651447,0.00003547554,0.0001161905,0.00001250459],"category_scores_gemma":[0.00001916948,0.0001176882,0.00005251972,0.0000817764,0.0001546869,0.0001565388,0.000004210426,0.0001004908,0.000004904676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002170295,"about_ca_system_score_gemma":0.00002150508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001631303,"about_ca_topic_score_gemma":0.0001892117,"domain_scores_codex":[0.9986662,0.00008361258,0.0005192596,0.0003450579,0.0002113861,0.0001745379],"domain_scores_gemma":[0.9991346,0.0004622657,0.0001026151,0.0001224946,0.00003804479,0.0001399865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002338124,0.000170165,0.9841512,0.0002819272,0.00008981238,0.0001028237,0.0009364299,0.000008511314,0.00344058,0.0002278796,5.719622e-7,0.008251943],"study_design_scores_gemma":[0.007950532,0.0007051551,0.9860117,0.001256694,0.0002082217,0.0000954205,0.00001045346,0.00002060876,0.003519381,0.00008343456,0.00001167576,0.0001267096],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985656,0.0001207121,0.0002070286,0.0002659156,0.00003929373,0.0005406461,0.0001334267,0.00001869669,0.0001086882],"genre_scores_gemma":[0.9839996,0.0151169,0.0005386167,0.0002081121,0.00001154538,0.00002100647,0.0000262145,0.00001286035,0.00006516807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01499619,"threshold_uncertainty_score":0.4799187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03236027177779266,"score_gpt":0.3260389961048662,"score_spread":0.2936787243270735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}