{"id":"W2516309500","doi":"10.1097/tp.0000000000001394","title":"Influence of Donor and Recipient CYP3A4, CYP3A5, and ABCB1 Genotypes on Clinical Outcomes and Nephrotoxicity in Liver Transplant Recipients","year":2016,"lang":"en","type":"article","venue":"Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Particle Physics","funders":"","keywords":"Hazard ratio; Medicine; Calcineurin; Internal medicine; Tacrolimus; Confidence interval; Renal function; Gastroenterology; Proportional hazards model; Population; Nephrotoxicity; Kidney transplantation; Transplantation; Liver transplantation; Urology; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007989401,0.0002088588,0.00027367,0.0003237524,0.0001539418,0.000401959,0.0001363994,0.0002183366,0.0009722878],"category_scores_gemma":[0.001992292,0.0001156731,0.0004047212,0.0003561906,0.0002799357,0.0002074056,0.0001852231,0.0003144446,0.0001431921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001719031,"about_ca_system_score_gemma":0.0001801075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006615429,"about_ca_topic_score_gemma":0.0006177088,"domain_scores_codex":[0.9995073,0.0002131473,0.00004807653,0.00008181143,0.00008329281,0.00006642278],"domain_scores_gemma":[0.9983054,0.0005630474,0.0007114176,0.0001168679,0.00007476005,0.0002284956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005959568,0.00002468694,0.996772,0.000006600834,0.00008865244,0.00006627671,0.00002496032,0.00006329985,0.0004700218,0.000008219244,0.00001314055,0.00186619],"study_design_scores_gemma":[0.000008360244,0.0001911859,0.9989929,0.000002013889,0.00006783797,0.0003059822,0.00003183231,0.0001727794,0.0001613034,0.00002024566,0.00004340277,0.000002310706],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996389,0.0001979441,0.00004475178,0.000007245047,0.000001285089,9.269892e-7,0.00002437181,0.000001001342,0.00008350701],"genre_scores_gemma":[0.9998776,0.00003129657,0.00002464107,0.000004011198,0.000003569845,9.150355e-7,0.00002828316,8.208851e-7,0.00002880042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009722878,"threshold_uncertainty_score":0.004225254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03236027177779266,"score_gpt":0.3260389961048662,"score_spread":0.2936787243270735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}