{"id":"W2516407760","doi":"10.1016/j.humimm.2016.07.168","title":"P103 Crosslinking immunogenetics to pharmacogenetics: Fc<mml:math xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" altimg=\"si1.gif\" overflow=\"scroll\"><mml:mrow><mml:mi>γ</mml:mi></mml:mrow></mml:math>RIIIa polymorphism predicts response to Rituximab therapy in mantle cell lymphoma","year":2016,"lang":"lv","type":"article","venue":"Human Immunology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Rituximab; Antibody-dependent cell-mediated cytotoxicity; Mantle cell lymphoma; Lymphoma; Medicine; Internal medicine; Immunology; Oncology; Antibody; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006583372,0.0004780233,0.0003093707,0.0006942611,0.0003042145,0.0009181179,0.000419885,0.0009100335,0.06830538],"category_scores_gemma":[0.001645124,0.0003415563,0.0004438994,0.0004723357,0.000223586,0.0003000288,0.0003192289,0.0009305585,0.01205374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006891096,"about_ca_system_score_gemma":0.0003688768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002841965,"about_ca_topic_score_gemma":0.002906108,"domain_scores_codex":[0.9995139,0.0001760056,0.00003169435,0.00008973042,0.0001120809,0.00007659782],"domain_scores_gemma":[0.999549,0.0002256971,0.00004939361,0.00009642314,0.00003694559,0.00004244474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00281151,0.0008855271,0.04072155,0.0004767323,0.0003945861,0.00206224,0.0003777155,0.003004174,0.4113233,0.00899455,0.1687635,0.3601848],"study_design_scores_gemma":[0.0009397019,0.001047419,0.09569633,0.0003514297,0.0004102408,0.007431233,0.0001770227,0.01113507,0.6285173,0.00711266,0.2470899,0.00009178667],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5814279,0.003578409,0.1248938,0.009381867,0.0009872533,0.001004085,0.0184845,0.0122579,0.2479843],"genre_scores_gemma":[0.8595578,0.001456475,0.04442518,0.002883752,0.0002685648,0.000527358,0.009773207,0.001886786,0.07922084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06830538,"threshold_uncertainty_score":0.2285042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02581064954540687,"score_gpt":0.2837742861683921,"score_spread":0.2579636366229852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}