{"id":"W2516852464","doi":"10.1186/s40814-016-0087-6","title":"Progesterone supplementation for HIV-positive pregnant women on protease inhibitor-based antiretroviral regimens (the ProSPAR study): a study protocol for a pilot randomized controlled trial","year":2016,"lang":"en","type":"article","venue":"Pilot and Feasibility Studies","topic":"Pregnancy and Medication Impact","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Western University; St. Michael's Hospital; Mount Sinai Hospital; Maple Leaf Medical Clinic; Women's College Hospital; St Joseph's Health Care; University of Toronto; Toronto General Hospital","funders":"Canadian HIV Trials Network, Canadian Institutes of Health Research; Canadian Institutes of Health Research; Ontario HIV Treatment Network; Canadian Foundation for AIDS Research","keywords":"Randomized controlled trial; Protease inhibitor (pharmacology); Medicine; Human immunodeficiency virus (HIV); Pregnancy; Protocol (science); Obstetrics; Gynecology; Antiretroviral therapy; Internal medicine; Viral load; Virology; Alternative medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004906667,0.0004273875,0.001890599,0.0001186142,0.0004897513,0.00004369091,0.0001059046,0.00003948639,0.000009996748],"category_scores_gemma":[0.005631921,0.0001879725,0.0002306379,0.0001234418,0.0004612146,0.0001432538,0.00005570754,0.0001167164,0.000001829484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003251059,"about_ca_system_score_gemma":0.0003106663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008723751,"about_ca_topic_score_gemma":0.00001654111,"domain_scores_codex":[0.9961776,0.000920109,0.001100721,0.0007520307,0.0005354618,0.0005141155],"domain_scores_gemma":[0.9957041,0.002509044,0.0005924903,0.0005030789,0.0005083027,0.000182956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9583939,0.01837805,0.01254935,0.0005122335,0.001379518,0.000002531443,0.006517327,1.131395e-7,0.0003722961,0.00003425749,0.0004424756,0.001417905],"study_design_scores_gemma":[0.8410853,0.1489319,0.003506366,0.0009004169,0.0006861598,9.554685e-7,0.003560356,0.00002459478,0.0008173775,0.0002356327,0.00005184758,0.0001990914],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.418635,0.00003391438,0.0003294756,0.002501584,0.00008308527,0.578289,0.00005642936,0.00005942638,0.00001201401],"genre_scores_gemma":[0.4960765,0.000002408667,0.00007936247,0.00009951062,0.00015181,0.503106,0.000006145299,0.00001708154,0.0004611888],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.1305539,"threshold_uncertainty_score":0.7665298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1408551942032951,"score_gpt":0.428039384314137,"score_spread":0.2871841901108419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}