{"id":"W2516852464","doi":"10.1186/s40814-016-0087-6","title":"Progesterone supplementation for HIV-positive pregnant women on protease inhibitor-based antiretroviral regimens (the ProSPAR study): a study protocol for a pilot randomized controlled trial","year":2016,"lang":"en","type":"article","venue":"Pilot and Feasibility Studies","topic":"Pregnancy and Medication Impact","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Western University; St. Michael's Hospital; Mount Sinai Hospital; Maple Leaf Medical Clinic; Women's College Hospital; St Joseph's Health Care; University of Toronto; Toronto General Hospital","funders":"Canadian HIV Trials Network, Canadian Institutes of Health Research; Canadian Institutes of Health Research; Ontario HIV Treatment Network; Canadian Foundation for AIDS Research","keywords":"Randomized controlled trial; Protease inhibitor (pharmacology); Medicine; Human immunodeficiency virus (HIV); Pregnancy; Protocol (science); Obstetrics; Gynecology; Antiretroviral therapy; Internal medicine; Viral load; Virology; Alternative medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03843156,0.005716432,0.009878376,0.002206505,0.00306892,0.003371558,0.003340277,0.007301043,0.03581573],"category_scores_gemma":[0.02843691,0.003133546,0.004280082,0.002853117,0.004044536,0.003407692,0.001945268,0.005276046,0.005752374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003501059,"about_ca_system_score_gemma":0.01465413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002479659,"about_ca_topic_score_gemma":0.004865727,"domain_scores_codex":[0.9731787,0.01968857,0.002160715,0.001395761,0.001689055,0.001887241],"domain_scores_gemma":[0.9877743,0.0040374,0.002651438,0.001503486,0.002072108,0.001961328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9460422,0.01443825,0.0008081511,0.01158251,0.001205688,0.0002049515,0.000280956,0.001064426,0.001447005,0.002039524,0.005128573,0.01575766],"study_design_scores_gemma":[0.968006,0.02302857,0.000766828,0.0008583756,0.0003801026,0.0000268399,0.00006912624,0.0006755047,0.0002516077,0.0006444392,0.005256225,0.00003650066],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.003164437,0.0003061713,0.0008839461,0.0001427595,0.0001971514,0.9944187,0.0004560685,0.0000575668,0.0003732001],"genre_scores_gemma":[0.003199062,0.0001958515,0.002561722,0.0001550183,0.000047129,0.993477,0.0000895705,0.000004147188,0.0002704669],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.03843156,"threshold_uncertainty_score":0.2032479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1408551942032951,"score_gpt":0.428039384314137,"score_spread":0.2871841901108419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}