{"id":"W2516922090","doi":"10.1371/journal.pgen.1006246","title":"Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation","year":2016,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eberhard Karls Universität Tübingen; Irish Research Council; Deutscher Akademischer Austauschdienst; National Institutes of Health; Irish Research Council for Science, Engineering and Technology; Science Foundation Ireland; Deutsche Forschungsgemeinschaft; National Institute of Allergy and Infectious Diseases; Horizon 2020; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs; Foundation for the National Institutes of Health","keywords":"Staphylococcus lugdunensis; Biology; Locus (genetics); Gene duplication; Virulence; Coagulase; Genetics; Pathogen; Gene; Microbiology; Staphylococcus aureus; Staphylococcus; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001267682,0.000279714,0.0003515644,0.0002349153,0.0001516116,0.0003100776,0.0002565635,0.0003543789,0.0005813881],"category_scores_gemma":[0.0002317171,0.0001304984,0.0002933566,0.0001833542,0.000215462,0.0001036793,0.0004884343,0.0004310542,0.0002320685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004463475,"about_ca_system_score_gemma":0.0002367334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002602241,"about_ca_topic_score_gemma":0.002401294,"domain_scores_codex":[0.9997843,0.00003534164,0.00002570662,0.00004243198,0.00006655655,0.00004574888],"domain_scores_gemma":[0.9998461,0.0000321181,0.00004033218,0.00002161026,0.00001598568,0.00004384522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009446171,0.00003597655,0.001156184,0.00001772346,0.000006058538,0.0001691648,0.0000320492,0.00006535406,0.9971392,0.00006504429,0.00002472703,0.001194059],"study_design_scores_gemma":[0.00004162821,0.0008176836,0.07661799,0.00002165829,0.00003709827,0.002288358,0.0003709785,0.006193285,0.9106011,0.0001332769,0.002839462,0.00003741974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990863,0.0001109714,0.0003357769,0.0000461606,0.000006388393,0.000005739072,0.00007400923,0.00001306854,0.0003215293],"genre_scores_gemma":[0.9977068,0.00006471943,0.0007869885,0.00003918598,0.000002740028,0.000008680729,0.000279858,0.00001412695,0.001096906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002602241,"threshold_uncertainty_score":0.00517416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03494713993939998,"score_gpt":0.2980619932674469,"score_spread":0.263114853328047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}