{"id":"W2516922090","doi":"10.1371/journal.pgen.1006246","title":"Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation","year":2016,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Eberhard Karls Universität Tübingen; Irish Research Council; Deutscher Akademischer Austauschdienst; National Institutes of Health; Irish Research Council for Science, Engineering and Technology; Science Foundation Ireland; Deutsche Forschungsgemeinschaft; National Institute of Allergy and Infectious Diseases; Horizon 2020; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs; Foundation for the National Institutes of Health","keywords":"Staphylococcus lugdunensis; Biology; Locus (genetics); Gene duplication; Virulence; Coagulase; Genetics; Pathogen; Gene; Microbiology; Staphylococcus aureus; Staphylococcus; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001780077,0.0001272512,0.0002185748,0.0001504651,0.000069102,0.00001457357,0.0001009101,0.00007161365,0.0000132576],"category_scores_gemma":[0.0004332562,0.0000900366,0.00006083532,0.0002646068,0.0001187204,0.00003785503,0.00007177662,0.00008646859,0.000007069508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001489823,"about_ca_system_score_gemma":0.0001038566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000691584,"about_ca_topic_score_gemma":0.00004451371,"domain_scores_codex":[0.9987096,0.00005631688,0.0003574058,0.0003013373,0.0003484993,0.0002268004],"domain_scores_gemma":[0.9986537,0.0004970329,0.000116027,0.0002901288,0.0003505285,0.00009254475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000299361,0.000337528,0.04807181,0.0003052752,0.00002127999,6.771674e-7,0.0004894291,0.00001352804,0.9466153,0.0006685148,0.00004867023,0.00312857],"study_design_scores_gemma":[0.002568245,0.0005009836,0.1104859,0.0006572441,0.00007171628,0.00000520129,0.001401113,0.001176359,0.8815271,0.0002537423,0.001178853,0.0001736054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921013,0.0003490755,0.0004397555,0.004894585,0.00002229777,0.001856966,0.0001832032,0.00001491659,0.0001379373],"genre_scores_gemma":[0.9977059,0.0002575316,0.001484618,0.000118574,0.0001016355,0.0002123166,0.00004142589,0.00002163482,0.0000563791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06508831,"threshold_uncertainty_score":0.3671586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03494713993939998,"score_gpt":0.2980619932674469,"score_spread":0.263114853328047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}