{"id":"W2516975515","doi":"10.4049/jimmunol.1600828","title":"Endocytosis of Cytotoxic Granules Is Essential for Multiple Killing of Target Cells by T Lymphocytes","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Cytotoxic T cell; Endocytosis; Cell biology; Chemistry; Biology; Cell; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001337304,0.0002673515,0.0003583693,0.0001301603,0.0001733108,0.0005954984,0.0001940479,0.0003709944,0.0008308454],"category_scores_gemma":[0.0001973675,0.0001726022,0.0003420626,0.0001011457,0.0002786015,0.0003668246,0.0004137328,0.0006840368,0.0004886073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004213121,"about_ca_system_score_gemma":0.0002905592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003468137,"about_ca_topic_score_gemma":0.0003331333,"domain_scores_codex":[0.999795,0.00001920413,0.00002948901,0.00004020772,0.00005908817,0.00005698159],"domain_scores_gemma":[0.9997484,0.00003525965,0.0000788647,0.0000558319,0.0000238836,0.00005774225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008737269,0.00001289962,0.0003633973,0.00001702112,0.00000278175,0.0000878166,0.000005007526,0.00003785848,0.9985558,0.0001110309,0.00001825793,0.0007008211],"study_design_scores_gemma":[0.00002270244,0.0001323634,0.01234092,0.000006052873,0.0000189121,0.0007970592,0.00002639395,0.001125481,0.9840731,0.0001150894,0.001336565,0.000005321364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942275,0.00107023,0.003598531,0.00008246617,0.00002302178,0.0000129344,0.0001304491,0.0001187793,0.0007360079],"genre_scores_gemma":[0.9976417,0.0002737264,0.001077701,0.00002184195,0.000005703468,0.000009410051,0.0001649583,0.0000206885,0.0007843874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008308454,"threshold_uncertainty_score":0.003056884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008232895648543927,"score_gpt":0.2197518557248107,"score_spread":0.2115189600762668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}