{"id":"W2517003590","doi":"10.1139/apnm-2016-0326","title":"Inhibition of Akt2 phosphorylation abolishes the calorie restriction-induced improvement in insulin-stimulated glucose uptake by rat soleus muscle","year":2016,"lang":"en","type":"article","venue":"Applied Physiology Nutrition and Metabolism","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Aging","keywords":"Soleus muscle; Phosphorylation; AKT2; Internal medicine; Endocrinology; Skeletal muscle; Insulin; Calorie restriction; Chemistry; Protein kinase B; Glucose uptake; Biochemistry; Biology; Medicine; AKT1","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001677164,0.0006103488,0.0004690255,0.0002674637,0.0001513584,0.0002558773,0.0003032251,0.0002231347,0.001694771],"category_scores_gemma":[0.000099713,0.0002557261,0.0003921556,0.0002255742,0.0002877934,0.000204012,0.000196276,0.000737449,0.0004401822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002697308,"about_ca_system_score_gemma":0.0004166593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001105449,"about_ca_topic_score_gemma":0.001978496,"domain_scores_codex":[0.9998716,0.00001590853,0.0000202038,0.00002398991,0.0000228898,0.00004531486],"domain_scores_gemma":[0.9998986,0.00001281328,0.00002534116,0.00001242409,0.00000849864,0.00004240419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001160305,0.0002029802,0.0001852592,0.0000729476,0.00001551511,0.00003430459,0.00001102103,0.00008236302,0.9961919,0.00008512221,0.0000571707,0.001901089],"study_design_scores_gemma":[0.0001232767,0.001515345,0.004614951,0.00000834405,0.00003360802,0.0001312324,0.00001628192,0.0006812463,0.9915656,0.00003092531,0.001273372,0.00000585285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960958,0.0009797309,0.001152749,0.0000872317,0.00004591158,0.00003703717,0.0003725718,0.0001150455,0.00111388],"genre_scores_gemma":[0.9929971,0.001262337,0.002094656,0.00007990056,0.00001990214,0.0000775493,0.0008419398,0.00004847573,0.002578126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001694771,"threshold_uncertainty_score":0.005669594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00773604151894938,"score_gpt":0.2186705535940306,"score_spread":0.2109345120750813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}