{"id":"W2517415615","doi":"10.1371/journal.pone.0161035","title":"Identification and Localization of the Cyclic Nucleotide Phosphodiesterase 10A in Bovine Testis and Mature Spermatozoa","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Centre Hospitalier Universitaire de Québec; Université Laval","keywords":"PDE10A; Adenylyl cyclase; Phosphodiesterase; Biology; Cyclic nucleotide; Cyclic nucleotide phosphodiesterase; Second messenger system; Gene isoform; Cyclic adenosine monophosphate; Guanine nucleotide exchange factor; Intracellular; Biochemistry; Nucleotide; Gene; Cell biology; Signal transduction; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007341841,0.00006806818,0.00008226241,0.00002498884,0.00003779177,0.00001126816,0.00004172602,0.00006677092,0.000008536451],"category_scores_gemma":[0.0001050092,0.00004304139,0.00001340743,0.00006670819,0.00008844008,0.000009377116,0.00004931082,0.00002625097,0.000001480467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008215408,"about_ca_system_score_gemma":0.000009941852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000788881,"about_ca_topic_score_gemma":0.00005139899,"domain_scores_codex":[0.9994989,0.00003365447,0.0001575297,0.0001555973,0.0000849883,0.00006930895],"domain_scores_gemma":[0.9996598,0.00001212629,0.00008196635,0.0001719131,0.00004844042,0.00002569278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004834327,0.00009761026,0.1241338,0.00004294299,0.0000160832,2.126776e-7,0.00004720379,0.000002924859,0.8745808,0.00003644878,0.0001207104,0.0008729537],"study_design_scores_gemma":[0.0004637043,0.00004016768,0.2049283,0.0001498657,0.0000206673,0.000003363088,0.00001633637,0.0002083338,0.7936794,0.00009707476,0.000325242,0.00006759648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982137,0.0004790484,0.0004284379,0.0006247131,0.00003270546,0.0001546945,0.0000134139,0.000005708314,0.00004756079],"genre_scores_gemma":[0.9986826,0.0004115625,0.00008149783,0.0001294132,0.00002723788,0.000007738465,0.00001456893,0.000008284755,0.0006370977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08090144,"threshold_uncertainty_score":0.1755177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009916473712330958,"score_gpt":0.1984052689982723,"score_spread":0.1884887952859414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}