{"id":"W2517542844","doi":"10.1016/j.bbrc.2016.08.112","title":"Synchrotron FTIR microspectroscopy reveals early adipogenic differentiation of human mesenchymal stem cells at single-cell level","year":2016,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Spectroscopy Techniques in Biomedical and Chemical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Light Source (Canada)","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Mesenchymal stem cell; Adipogenesis; Chemistry; Fourier transform infrared spectroscopy; Synchrotron; Stem cell; Cell biology; Cell; Cellular differentiation; Biophysics; Biology; Biochemistry; Optics; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004663339,0.000232794,0.0002996417,0.0001056906,0.0003193964,0.00003678732,0.001257835,0.0003431583,0.00005673729],"category_scores_gemma":[0.0001505062,0.0001635325,0.000174431,0.0003455377,0.00236844,0.00001166152,0.001820745,0.0003736356,0.00002852805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001528711,"about_ca_system_score_gemma":0.00006572557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000431388,"about_ca_topic_score_gemma":0.000006528804,"domain_scores_codex":[0.9972907,0.0002818645,0.0004488075,0.0006053161,0.0007037715,0.0006695664],"domain_scores_gemma":[0.9973798,0.0003179373,0.0001158774,0.001438023,0.0003688984,0.0003794801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001289571,0.0006885198,0.0005647962,0.00006002255,0.00003508173,4.813655e-7,0.00001614993,1.754329e-9,0.9927964,0.0007729008,0.004233649,0.0007030412],"study_design_scores_gemma":[0.0005201976,0.001001274,0.001250412,0.00009363026,0.00001599688,0.000001878588,0.00001091541,0.000004293669,0.9937803,0.00113486,0.001973995,0.0002122208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965121,0.0009143116,0.0002308356,0.0009231552,0.00001783469,0.0003729993,0.0001813415,0.00002856276,0.0008189246],"genre_scores_gemma":[0.9938357,0.001364736,0.001436751,0.00002791433,0.0001324145,0.0001116981,0.0001021036,0.00003049899,0.002958162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002676314,"threshold_uncertainty_score":0.8726617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06853371960153808,"score_gpt":0.3629513975640051,"score_spread":0.294417677962467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}