{"id":"W2517731749","doi":"10.1038/srep31675","title":"hCG-induced Sprouty2 mediates amphiregulin-stimulated COX-2/PGE2 up-regulation in human granulosa cells: a potential mechanism for the OHSS","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Zhengzhou University; First Affiliated Hospital of Zhengzhou University; National Natural Science Foundation of China","keywords":"Amphiregulin; Gene knockdown; Epidermal growth factor; Internal medicine; Endocrinology; Signal transduction; Human chorionic gonadotropin; Cell biology; Chemistry; Biology; Cancer research; Receptor; Cell culture; Medicine; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001412348,0.0002632599,0.0002861033,0.0001854162,0.00016175,0.0002176164,0.00009501071,0.0002036993,0.0009934632],"category_scores_gemma":[0.0001224773,0.00009954636,0.000383588,0.000128613,0.0002760094,0.0001495815,0.0002680233,0.0003892336,0.0001868542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002068084,"about_ca_system_score_gemma":0.0001823633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004337109,"about_ca_topic_score_gemma":0.0006287175,"domain_scores_codex":[0.9999052,0.00002090617,0.00001007095,0.00001640158,0.00002219684,0.00002527418],"domain_scores_gemma":[0.999936,0.000008607609,0.00002166162,0.000008052679,0.000007087134,0.00001861158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007543999,0.00007525931,0.003515285,0.0002110732,0.00002250633,0.001040636,0.00006643656,0.00006158199,0.9906728,0.0001804711,0.0001234458,0.003276091],"study_design_scores_gemma":[0.0002001033,0.001196773,0.1011533,0.00003469592,0.00008649319,0.002291759,0.0002876337,0.001080413,0.8869249,0.0002486908,0.006482185,0.00001297061],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915208,0.005273321,0.001615416,0.0002416071,0.00005422887,0.0000788875,0.0002776421,0.00003409113,0.0009039339],"genre_scores_gemma":[0.9945953,0.002005952,0.001088306,0.0001313063,0.00003005436,0.00009483436,0.0004295692,0.000005603411,0.001619156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009934632,"threshold_uncertainty_score":0.003323436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01721904448818822,"score_gpt":0.27691493156338,"score_spread":0.2596958870751918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}