{"id":"W2517975797","doi":"10.1039/c6tb00927a","title":"Hydrogels bearing bioengineered mimetic embryonic microenvironments for tumor reversion","year":2016,"lang":"en","type":"article","venue":"Journal of Materials Chemistry B","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatoon Medical Imaging; University of Saskatchewan","funders":"National Natural Science Foundation of China","keywords":"Embryonic stem cell; Reversion; Melanoma; Tumor microenvironment; Cancer research; Cell biology; Biology; Phenotype; Tumor cells; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008936894,0.0002627156,0.00008220488,0.0001178397,0.00005498818,0.0001470373,0.0001013257,0.0001585996,0.0008653863],"category_scores_gemma":[0.00008174546,0.00007853616,0.0001282064,0.00005940003,0.0000898747,0.0001552326,0.00008781069,0.0002204039,0.0001365662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001242569,"about_ca_system_score_gemma":0.0001119858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000158018,"about_ca_topic_score_gemma":0.0003801658,"domain_scores_codex":[0.9999582,0.000005177036,0.000003223274,0.00001049156,0.00001342158,0.000009440773],"domain_scores_gemma":[0.9999385,0.00001368743,0.00002543286,0.000004956258,0.000005064733,0.0000124444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001029184,0.000006031685,0.00005022033,0.00001623876,0.000002194736,0.00002276436,0.000004103903,0.00008313353,0.998924,0.00008295866,0.00001320154,0.000784998],"study_design_scores_gemma":[0.000005076447,0.00006983906,0.000441848,0.000002379879,0.000007084851,0.00007329186,0.000004469322,0.0004776607,0.9975349,0.0000199334,0.001360816,0.000002578533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809115,0.002112431,0.01436923,0.00008215204,0.00007008653,0.00004875101,0.0002383557,0.0001270776,0.00204047],"genre_scores_gemma":[0.9899212,0.0009533528,0.007456687,0.00004848367,0.00001066685,0.00003840557,0.0001412435,0.00002496419,0.00140498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008653863,"threshold_uncertainty_score":0.002895057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00912539671280798,"score_gpt":0.236713384104465,"score_spread":0.2275879873916571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}