{"id":"W2518245700","doi":"10.1212/wnl.0000000000003217","title":"Efficacy and safety of deflazacort vs prednisone and placebo for Duchenne muscular dystrophy","year":2016,"lang":"en","type":"article","venue":"Neurology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Deflazacort; Placebo; Medicine; Prednisone; Duchenne muscular dystrophy; Clinical endpoint; Internal medicine; Adverse effect; Randomized controlled trial; Physical therapy; Gastroenterology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002170735,0.0006423043,0.001909913,0.0004425067,0.0003291643,0.0005824504,0.0006747086,0.001428885,0.003182238],"category_scores_gemma":[0.002417029,0.0003443226,0.001030429,0.0002794543,0.0007080649,0.0005617269,0.0001982224,0.001393543,0.0004688795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000512148,"about_ca_system_score_gemma":0.0006395357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000399223,"about_ca_topic_score_gemma":0.0008110169,"domain_scores_codex":[0.9990309,0.0005714577,0.0000953831,0.0001064319,0.0001313179,0.00006445523],"domain_scores_gemma":[0.9979267,0.0008446305,0.0007500469,0.00006822195,0.0001034328,0.000306996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9111933,0.007937861,0.002448331,0.001108238,0.0009002789,0.00007323779,0.00007694331,0.0003219385,0.009331236,0.00006402423,0.0003959205,0.06614879],"study_design_scores_gemma":[0.5458843,0.4347796,0.01340793,0.0001310991,0.000890339,0.0001836401,0.00005988257,0.0005891943,0.002895284,0.00009947365,0.001056438,0.00002281433],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786745,0.01823153,0.0003535029,0.0004860851,0.0002193311,0.0007066175,0.0003959339,0.0000583565,0.0008740516],"genre_scores_gemma":[0.994303,0.003527102,0.0005430094,0.0002695896,0.0002379197,0.0004098018,0.0002264576,0.00000571838,0.0004774438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003182238,"threshold_uncertainty_score":0.01148009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005209591311673651,"score_gpt":0.2182133769266051,"score_spread":0.2130037856149314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}