{"id":"W2518584643","doi":"10.1139/gen-2016-0069","title":"The <i>HtrA2 Drosophila</i> model of Parkinson’s disease is suppressed by the pro-survival <i>Bcl-2</i> <i>Buffy</i>","year":2016,"lang":"en","type":"article","venue":"Genome","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland","keywords":"Biology; Drosophila melanogaster; Buffy coat; Caspase; Phenotype; Dopaminergic; Loss function; Cell biology; Apoptosis; Programmed cell death; Genetics; Neuroscience; Immunology; Gene; Dopamine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009955586,0.0006392938,0.0002700434,0.0004633207,0.0003359962,0.0003344941,0.0003503481,0.0004799112,0.002724911],"category_scores_gemma":[0.00005725941,0.0002143547,0.0003731613,0.0002454219,0.0003660406,0.0002197213,0.0003250833,0.001081034,0.0007386943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004763315,"about_ca_system_score_gemma":0.0002385106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001749539,"about_ca_topic_score_gemma":0.003660387,"domain_scores_codex":[0.9998641,0.00001713263,0.00001589088,0.00003581762,0.00004531218,0.00002177497],"domain_scores_gemma":[0.9998802,0.00001045969,0.00004772324,0.00001273646,0.000008743055,0.0000401642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006852428,0.00002521822,0.000099489,0.00002648946,0.000007546536,0.00008331276,0.000009340268,0.00004094352,0.9987375,0.0001893126,0.0000892354,0.000622981],"study_design_scores_gemma":[0.00006023325,0.0002666554,0.004862241,0.00001375151,0.00003068923,0.0007855908,0.0000382413,0.001577466,0.9830189,0.00009128883,0.009244163,0.00001065681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836919,0.001223188,0.005383946,0.0004097539,0.0001082508,0.00008798813,0.002752484,0.000346977,0.005995533],"genre_scores_gemma":[0.9719672,0.0009573019,0.006819095,0.0001770858,0.00002072672,0.0001190258,0.002785841,0.0001451008,0.01700851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002724911,"threshold_uncertainty_score":0.009115756,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0100888580868709,"score_gpt":0.2115190254282501,"score_spread":0.2014301673413792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}