{"id":"W2518640581","doi":"10.2337/db16-0564","title":"Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1","year":2016,"lang":"en","type":"article","venue":"Diabetes","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"AMPK; Homeostasis; Mitochondrion; Glucose homeostasis; Internal medicine; Chemistry; Endocrinology; Medicine; Pharmacology; Biochemistry; Diabetes mellitus; Insulin resistance; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001090022,0.0003112846,0.0002737757,0.0003734444,0.0001245729,0.0001830841,0.0001409278,0.0002490898,0.002539621],"category_scores_gemma":[0.0001101175,0.0001227876,0.0003979402,0.0002119714,0.0002009467,0.0001889361,0.0002600151,0.0005193702,0.0003537502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001779016,"about_ca_system_score_gemma":0.0001715315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003836243,"about_ca_topic_score_gemma":0.001345549,"domain_scores_codex":[0.9999034,0.00002005035,0.00001046122,0.00001572027,0.00003034137,0.00001989041],"domain_scores_gemma":[0.9999133,0.000008539942,0.00003922653,0.00000749864,0.000009619486,0.00002177695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001139735,0.0001414049,0.0005013488,0.0001540666,0.00002845624,0.00004855582,0.00001013527,0.00009340974,0.9875573,0.0001032811,0.000113858,0.01010839],"study_design_scores_gemma":[0.0004013157,0.005032355,0.01592549,0.00003485306,0.00008131101,0.0004810372,0.00004431584,0.0006662452,0.9709333,0.0001525229,0.006232904,0.0000142976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838362,0.008119869,0.003626863,0.0004099016,0.00008162777,0.00006592627,0.0006173139,0.0001679665,0.003074245],"genre_scores_gemma":[0.99085,0.003905973,0.002487005,0.000207279,0.0000304298,0.00002659927,0.0004349224,0.0000177633,0.002040081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002539621,"threshold_uncertainty_score":0.008495927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059372990737976,"score_gpt":0.2355659313153445,"score_spread":0.2249722014079648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}