{"id":"W2518765238","doi":"10.1200/jco.2016.68.5776","title":"PANCREOX: A Randomized Phase III Study of Fluorouracil/Leucovorin With or Without Oxaliplatin for Second-Line Advanced Pancreatic Cancer in Patients Who Have Received Gemcitabine-Based Chemotherapy","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":291,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"American Society of Clinical Oncology","keywords":"Oxaliplatin; Medicine; Gemcitabine; Folinic acid; Fluorouracil; Regimen; Internal medicine; Clinical endpoint; Phases of clinical research; Progression-free survival; Pancreatic cancer; Chemotherapy; Oncology; Adverse effect; Performance status; Gastroenterology; Surgery; Cancer; Colorectal cancer; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002474582,0.001674223,0.002238143,0.0005074075,0.0004337849,0.001178545,0.0008613216,0.001412409,0.004658049],"category_scores_gemma":[0.001104755,0.0007838293,0.001275953,0.0004583048,0.001369441,0.0009580074,0.0006819814,0.002908957,0.0006710489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007317056,"about_ca_system_score_gemma":0.001590607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005990801,"about_ca_topic_score_gemma":0.001846772,"domain_scores_codex":[0.999411,0.000354242,0.00002928452,0.00007575715,0.00003435638,0.00009544287],"domain_scores_gemma":[0.9990513,0.0001571981,0.000153127,0.0000673576,0.00003383643,0.0005372006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9594315,0.02025953,0.001412057,0.0002530181,0.0004044757,0.00004950575,0.00005949574,0.0003306202,0.004641634,0.0001127465,0.0005390351,0.01250644],"study_design_scores_gemma":[0.9189016,0.07868323,0.001263239,0.000008880274,0.0001458321,0.0000271742,0.00001154305,0.0001993363,0.0003165328,0.00005663282,0.0003802369,0.000005652575],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914439,0.001244881,0.000542007,0.0003919908,0.0002386259,0.004487707,0.0005267918,0.00007153459,0.001052626],"genre_scores_gemma":[0.9846079,0.001637118,0.002137889,0.001140903,0.0003418519,0.006332355,0.001258383,0.00002611973,0.002517604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004658049,"threshold_uncertainty_score":0.01558268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09762290404530811,"score_gpt":0.4899991221354943,"score_spread":0.3923762180901862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}