{"id":"W2519097826","doi":"10.1111/cei.12866","title":"Efficacy, safety, tolerability and pharmacokinetics of a novel human immune globulin subcutaneous, 20%: a Phase 2/3 study in Europe in patients with primary immunodeficiencies","year":2016,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Baxalta","keywords":"Tolerability; Medicine; Adverse effect; Pharmacokinetics; Incidence (geometry); Internal medicine; Antibody; Gastroenterology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002588495,0.0007083569,0.001026612,0.000285983,0.0002194078,0.0007703336,0.0004347376,0.0008525175,0.0009431356],"category_scores_gemma":[0.001120732,0.000344291,0.00121496,0.000308311,0.0007459291,0.0005357012,0.0002109502,0.001514458,0.0002536342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005204706,"about_ca_system_score_gemma":0.0007686733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004590531,"about_ca_topic_score_gemma":0.0005903629,"domain_scores_codex":[0.999449,0.000340254,0.00002797393,0.00007482542,0.00004910167,0.00005885382],"domain_scores_gemma":[0.9993259,0.0001696739,0.0001818513,0.00005123842,0.00005357423,0.0002177491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5438747,0.07174125,0.03520613,0.001002207,0.002327162,0.0007320053,0.0007004649,0.004953316,0.1084278,0.0003951479,0.00252437,0.2281154],"study_design_scores_gemma":[0.2007951,0.7503154,0.03635881,0.00004991522,0.0005246222,0.0006474945,0.00007252441,0.001732826,0.007199356,0.0001300007,0.002140117,0.00003395108],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967637,0.001714989,0.0004601304,0.0001096697,0.00001938845,0.0003489452,0.0001400261,0.00003383609,0.000409405],"genre_scores_gemma":[0.9957706,0.001304393,0.0012298,0.0004222564,0.00005950464,0.000342897,0.0004858017,0.00001655643,0.0003681562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002588495,"threshold_uncertainty_score":0.01368946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02308697521316649,"score_gpt":0.3311179080327173,"score_spread":0.3080309328195508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}