{"id":"W2519270966","doi":"10.1016/j.cels.2016.08.008","title":"Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci","year":2016,"lang":"en","type":"article","venue":"Cell Systems","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"DNA damage; Biology; Phenomics; Saccharomyces cerevisiae; Computational biology; Genome; Functional genomics; Mutant; DNA; Genomics; Genetics; Context (archaeology); Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009489918,0.0001207265,0.0002110076,0.00008484846,0.00002137543,0.00001195535,0.0001149236,0.00004645593,0.000004615269],"category_scores_gemma":[0.000009484686,0.00008667282,0.00008319196,0.0001712126,0.00003638324,0.000004424127,0.00003718684,0.00002381728,0.000005398525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001616131,"about_ca_system_score_gemma":0.00001805338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000028247,"about_ca_topic_score_gemma":0.00002406537,"domain_scores_codex":[0.9992995,0.0000268222,0.0001909807,0.000230701,0.00008992501,0.0001620454],"domain_scores_gemma":[0.9994581,0.00001782398,0.00009614342,0.0003059382,0.00006534012,0.00005660584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002810203,0.00003815534,0.001107618,0.00006149762,0.0001931704,0.000001425171,0.0001842002,0.004445133,0.993732,0.00003260503,0.00003800885,0.0001380857],"study_design_scores_gemma":[0.0004799891,0.0002855246,0.0009213269,0.00004144948,0.0002304026,0.000001058186,0.001108792,0.0006339221,0.9933071,5.973689e-7,0.002797984,0.0001918323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9341311,0.000562018,0.06282502,0.000004602278,0.0001220104,0.00009808587,0.00003276857,0.000008862226,0.002215498],"genre_scores_gemma":[0.9986426,0.00006788361,0.0004895469,0.000002633047,0.00006508252,0.00001676392,0.00002192414,0.0000223805,0.0006712363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06451142,"threshold_uncertainty_score":0.3534415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0384747718759306,"score_gpt":0.2543623934573078,"score_spread":0.2158876215813772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}