{"id":"W2519301732","doi":"10.1074/jbc.m116.725929","title":"Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"EMD Serono; Biogen; Kommission für Technologie und Innovation; Monash University; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"B-cell activating factor; Tumor necrosis factor alpha; Antibody; B cell; Cancer research; Cell; Immunology; Biology; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001812195,0.000638714,0.0002899982,0.0003271252,0.00009097912,0.0001888097,0.0002127554,0.000396257,0.001518987],"category_scores_gemma":[0.00009447244,0.0001586308,0.0003605983,0.0001298598,0.0001725546,0.0001759572,0.0001653681,0.0006819259,0.0005150685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001825843,"about_ca_system_score_gemma":0.0001482801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001886403,"about_ca_topic_score_gemma":0.0003570947,"domain_scores_codex":[0.9997596,0.00003709245,0.00002445963,0.00005354246,0.00005287807,0.00007236996],"domain_scores_gemma":[0.9998748,0.00002802698,0.00004039585,0.00001634525,0.00001122085,0.00002922569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004213354,0.00003286002,0.00006599195,0.00002116403,0.000004050469,0.00002073851,0.00000467706,0.00001263469,0.9990085,0.00004886156,0.00002013042,0.0007182875],"study_design_scores_gemma":[0.00001844248,0.0005781052,0.001094014,0.000003705786,0.00001802861,0.0002395853,0.000006383447,0.000137249,0.9961177,0.00001690446,0.001767676,0.000002247187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879962,0.002731408,0.006795564,0.00007187302,0.00007856674,0.00007283191,0.0001664458,0.0001502474,0.001936995],"genre_scores_gemma":[0.9877628,0.002267807,0.005731864,0.0001202668,0.00004427991,0.0001251111,0.0006619339,0.00003154482,0.003254377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001518987,"threshold_uncertainty_score":0.005081534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03368177514695655,"score_gpt":0.2416815482785665,"score_spread":0.20799977313161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}