{"id":"W2519305629","doi":"10.2196/resprot.6346","title":"Protocol Outlines for Parts 1 and 2 of the Prospective Endoscopy III Study for the Early Detection of Colorectal Cancer: Validation of a Concept Based on Blood Biomarkers","year":2016,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Augustinus Fonden; Abbott Laboratories","keywords":"Colorectal cancer; Medicine; Protocol (science); Prospective cohort study; Medical physics; Cancer; Oncology; Internal medicine; Pathology; Alternative medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06590573,0.002823081,0.002746233,0.002570978,0.004547279,0.002438788,0.003573455,0.005649385,0.08836193],"category_scores_gemma":[0.06820782,0.002388564,0.003466499,0.002522138,0.002097503,0.002169376,0.003655243,0.004796128,0.03379519],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003980502,"about_ca_system_score_gemma":0.02117817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002721218,"about_ca_topic_score_gemma":0.004679194,"domain_scores_codex":[0.9632282,0.0254513,0.004166005,0.002589005,0.002889045,0.001676449],"domain_scores_gemma":[0.9455669,0.01723422,0.004890243,0.01229835,0.01642596,0.003584306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.08382917,0.01780384,0.01661001,0.02897184,0.0007470874,0.00211642,0.005780844,0.004997182,0.01673802,0.03793338,0.4922693,0.2922029],"study_design_scores_gemma":[0.0213254,0.0221652,0.03708043,0.01007327,0.0003742373,0.0008213217,0.001683018,0.002460326,0.007224792,0.01026529,0.8861314,0.0003953191],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.002462687,0.0003148042,0.01561189,0.0007706888,0.0007112272,0.9624035,0.009213691,0.0003054198,0.008206119],"genre_scores_gemma":[0.001327273,0.0002349438,0.01064846,0.0004508513,0.0000710695,0.983031,0.002232946,0.00002763953,0.001975751],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.08836193,"threshold_uncertainty_score":0.348547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1176892248812117,"score_gpt":0.4801875407096443,"score_spread":0.3624983158284327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}