{"id":"W2519329875","doi":"10.1097/01.hjh.0000500552.89974.b8","title":"OS 25-03 OVEREXPRESSION OF HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN F PREVENTS SYSTEMIC HYPERTENSION AND KIDNEY INJURY AND NORMALIZES RENAL RENIN-ANGIOTENSIN SYSTEM GENES EXPRESSION IN TYPE 2 DIABETIC DB/DB TRANSGENIC MICE","year":2016,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Endocrinology; Internal medicine; Kidney; Renin–angiotensin system; Angiotensin II; Medicine; Messenger RNA; Transgene; Molecular biology; Biology; Receptor; Blood pressure; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002641295,0.0006969612,0.0005811379,0.0007887656,0.0002372405,0.0004141341,0.0004606579,0.0004668269,0.002499996],"category_scores_gemma":[0.00009807826,0.0003025926,0.0004223168,0.0003085039,0.0004427419,0.0003040072,0.0001765331,0.0008863444,0.0008913564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002646364,"about_ca_system_score_gemma":0.0003282627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008504206,"about_ca_topic_score_gemma":0.001307737,"domain_scores_codex":[0.9997299,0.00003182027,0.00003726995,0.00005629833,0.00006771054,0.00007699151],"domain_scores_gemma":[0.9996262,0.00002011595,0.0001390576,0.00003258385,0.0000225149,0.000159474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006234358,0.0002378892,0.0002750469,0.00003627122,0.000008957506,0.0000656472,0.00001627477,0.00004407702,0.9973881,0.00007230668,0.00007326094,0.001158932],"study_design_scores_gemma":[0.0002721809,0.00270424,0.007589561,0.00002192215,0.00008058061,0.0005181681,0.0001272641,0.0008652956,0.9823881,0.00007572506,0.005343071,0.00001401947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935329,0.0007337251,0.002771799,0.000102843,0.00006195451,0.00005662571,0.000783013,0.0002513567,0.001705709],"genre_scores_gemma":[0.9751829,0.001738021,0.007208852,0.000189729,0.00004926846,0.0002168776,0.002624859,0.0001810429,0.01260848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002499996,"threshold_uncertainty_score":0.008363307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009690802579466239,"score_gpt":0.2089709956240658,"score_spread":0.1992801930445995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}