{"id":"W2519484468","doi":"10.1182/blood.v126.23.2938.2938","title":"Improvement of Quality of Response with Ibrutinib Plus Bendamustine/Rituximab Vs Placebo Plus Bendamustine/Rituximab for Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"","keywords":"Bendamustine; Chronic lymphocytic leukemia; Ibrutinib; Rituximab; Medicine; Ofatumumab; Internal medicine; Lymphoma; Placebo; Oncology; Leukemia; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002080461,0.0007202066,0.002156445,0.0005161468,0.0002084722,0.0006740749,0.0005261327,0.0006965293,0.004279413],"category_scores_gemma":[0.001234276,0.0004488983,0.001854786,0.0003812879,0.0007213221,0.0004175195,0.0004753635,0.001271274,0.0003820533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006350792,"about_ca_system_score_gemma":0.0005823522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004247148,"about_ca_topic_score_gemma":0.0007359627,"domain_scores_codex":[0.9986744,0.0007395985,0.0001207001,0.0001728659,0.000124912,0.0001675888],"domain_scores_gemma":[0.998884,0.0002976079,0.0003920176,0.00005573535,0.00004007321,0.0003304688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9683115,0.004175237,0.003513434,0.000300218,0.001372857,0.0000186147,0.00002713259,0.0004956864,0.004069844,0.00003846416,0.000158425,0.01751846],"study_design_scores_gemma":[0.4903516,0.4815128,0.02220532,0.00005692209,0.001852989,0.00005488734,0.00002823096,0.0008577011,0.001921025,0.000232512,0.0009031244,0.00002278294],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951161,0.002347777,0.0002630431,0.0001531414,0.00009410541,0.001000604,0.0004081384,0.00002332202,0.0005937345],"genre_scores_gemma":[0.9967594,0.0006994191,0.0003868443,0.0001479157,0.0001173099,0.00100506,0.0002561634,0.000003651439,0.0006244496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004279413,"threshold_uncertainty_score":0.01431602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05272534709758657,"score_gpt":0.3169892187142128,"score_spread":0.2642638716166262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}