{"id":"W2519922130","doi":"10.1016/bs.ampbs.2016.07.004","title":"The Impact of Gene Silencing on Horizontal Gene Transfer and Bacterial Evolution","year":2016,"lang":"en","type":"review","venue":"Advances in microbial physiology/Advances in Microbial Physiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Gene silencing; Biology; Horizontal gene transfer; Genetics; Gene; Pathogenicity island; Regulation of gene expression; Operon; Bacterial conjugation; Virulence; Cell biology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006432661,0.0006260468,0.0009294116,0.001028828,0.0001716162,0.00100529,0.0006561539,0.001087103,0.002195488],"category_scores_gemma":[0.0007379241,0.000213557,0.0003177977,0.001323373,0.0006972938,0.001239928,0.0007883181,0.001340664,0.0009807621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006130578,"about_ca_system_score_gemma":0.0009724907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006895895,"about_ca_topic_score_gemma":0.001130866,"domain_scores_codex":[0.9998229,0.00002285649,0.0000186519,0.00003630769,0.00007550434,0.00002390906],"domain_scores_gemma":[0.9996692,0.0001741157,0.0000505581,0.00001124815,0.00006908575,0.00002577052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008541821,0.00002837489,0.0002175283,0.01064211,0.00006535421,0.0001714273,0.00004403683,0.000344788,0.008763995,0.007003635,0.01188584,0.9607475],"study_design_scores_gemma":[0.00001374273,0.00008349267,0.001030916,0.002226709,0.0001006083,0.0007235811,0.00006728996,0.0001194113,0.003417515,0.003797111,0.9883979,0.00002177501],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001652861,0.9986624,0.0001670206,0.0002487917,0.0001717037,0.000001394324,0.00001055601,0.000003881736,0.0005689872],"genre_scores_gemma":[0.001140889,0.9978623,0.0001554916,0.0001857611,0.0001692908,0.000002612637,0.00001991545,0.000001547196,0.0004621792],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002195488,"threshold_uncertainty_score":0.007344604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009155520045642764,"score_gpt":0.3201250652864699,"score_spread":0.3109695452408271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}